Starts Jimmy Garapplo looks like he will suit up as the 49ers QB1 this week and he’s in store for a big game. The 49ers play the Colts on Sunday night football and if you’re replacing one of Allen, Prescott, Herbert, or Cousins, give Garoppolo a look. The Colts have allowed the 8th-most fantasy points to the position through 6 weeks (22.27). This has been skewed from Lamar’s 41.88 and Mills’ 8.22 fantasy point performances, but they allowed Brissett and Tannehill to score 14.76 and 23.48 fantasy points. Garoppolo fits somewhere in between this week and gets you at least 18.5-22 fantasy points.