Who Should I Start? Amon-Ra St. Brown or Kyren Williams

Friday, October 10, 6:01 PM

Detroit Lions wide receiver Amon-Ra St. Brown missed the team's Wednesday practice this week due to a wrist injury, but he practiced in full on Thursday and Friday and does not carry an injury designation into Detroit's Week 6 matchup with the Kansas City Chiefs. St. Brown has been one of the most productive wideouts in the NFL so far this season, recording 35 catches for 407 yards and six touchdowns through five games. Kansas City has fielded a stingy pass defense so far this season, allowing the ninth-fewest passing yards (999) and fourth-fewest number of passing touchdowns (five) in the NFL. Still, St. Brown should see a significant target volume as the clear number one option in the Lions' passing game for quarterback Jared Goff. St. Brown profiles as a must-start fantasy wide receiver in Week 6 against the Chiefs.

Saturday, October 11, 12:01 AM

Los Angeles Rams running back Kyren Williams is gearing up for a very favorable matchup against the Baltimore Ravens in Week 6. Williams is coming off his best game of the year, in which he totaled 65 rushing yards, 66 receiving yards, and two touchdowns on a season-high 91 percent snap share. He has double-digit fantasy points (PPR) in all five games so far, including strong outings against tough defenses like the Eagles and 49ers. His 91 percent snap share indicates that he has a firm grasp on the lead-back role, and he should be able to take advantage of a favorable matchup on Sunday. Baltimore has allowed the sixth-most rushing yards, third-most receptions, and third-most fantasy points to opposing running backs in 2025. As a result, Williams is a mid-range RB1 this week.