Who Should I Start? Baker Mayfield or Kyler Murray

Sunday, October 12, 9:52 PM

Tampa Bay Buccaneers quarterback Baker Mayfield led his team to its fifth win of the season in Week 6, beating the San Francisco 49ers 30-19. Mayfield completed 17 of his 23 pass attempts for 256 yards and two touchdowns without throwing an interception and added 14 rushing yards on three carries. The 30-year-old has now thrown for 1,309 yards and 12 touchdowns in his first six games of 2025. Tampa Bay entered Week 6 without wide receivers Mike Evans (hamstring), Chris Godwin (leg), and Jalen McMillan (neck), and then lost star rookie wideout Emeka Egbuka (hamstring) to a hamstring injury during the game. It's currently unclear how long the Buccaneers will be without their top four wide receivers. Regardless, Mayfield has proven himself to be a worthy fantasy QB1 on a week-to-week basis.

Wednesday, October 15, 5:55 PM

Arizona Cardinals quarterback Kyler Murray (foot), who missed last week's loss to the Indianapolis Colts on Sunday, returned to practice on Wednesday and was limited, according to Tom Pelissero of NFL Network. Although it's good news that the 28-year-old signal-caller is on the practice field, he's dealing with a mid-foot sprain and is not a lock to return in Week 7 against the visiting Green Bay Packers. Veteran Jacoby Brissett's strong performance in Murray's absence last Sunday could also lead the Cardinals to play it safe with Murray this week and hold him out again as a precaution. It sounds like Arizona has no plans to rush Murray back into action, so fantasy managers need to have a backup plan in place in case he misses a second straight start. Through five games played, Murray has been a disappointment as a QB1 option in fantasy, ranking 24th among all QBs with an average of 19.1 fantasy points per game.