Who Should I Start? Brandon Aiyuk or Rome Odunze

Wednesday, November 5, 6:04 PM

San Francisco 49ers head coach Kyle Shanahan said on Wednesday that he's "pretty confident" that wide receiver Brandon Aiyuk (knee) will play at some point this season, according to David Lombardi of The San Francisco Standard. However, the 49ers are still waiting for Aiyuk to "hit certain markers" on GPS speed measurements before opening his 21-day practice window. Once Aiyuk returns to practice, the team will have 21 days to officially activate him from the Physically Unable to Perform list. Despite the optimism, reports on Monday suggested that the 27-year-old former first-rounder wasn't close to a return to practice, so fantasy managers who have been stashing Aiyuk all year shouldn't get their hopes up. Aiyuk suffered a torn ACL and MCL in Week 7 of last year and probably won't be back in games for the 49ers until December.

Thursday, November 6, 4:09 PM

Chicago Bears wide receiver Rome Odunze (ankle/heel) practiced in a limited capacity on Thursday after being held out on Wednesday, per The Athletic's Kevin Fishbain. Odunze followed a similar practice pattern last week and was able to play in Week 9, so he appears to be trending toward playing in Week 10 against the New York Giants. The 23-year-old is coming off his worst game of the season against the Cincinnati Bengals, as he was held without a reception on three targets. Odunze has been much better for the season overall, recording 31 catches for 473 yards and five touchdowns on 59 targets across eight games. Assuming he's cleared to play, Odunze profiles as a must-start fantasy wide receiver in Week 10 against the Giants.