Who Should I Start? Christian McCaffrey or Jameson Williams

Sunday, September 14, 8:39 PM

San Francisco 49ers running back Christian McCaffrey rushed for 55 yards on 13 carries during Sunday's Week 2 victory over the New Orleans Saints. He also caught six of seven targets for an additional 53 receiving yards and one receiving touchdown. Although the veteran playmaker didn't quite eclipse the 100-yard mark, he made up for it by scoring his first touchdown of the 2025 campaign. He also served as a very valuable and dependable pass-catching option for quarterback Mac Jones amidst the injury to Brock Purdy (shoulder). McCaffrey has wasted no time making a big impact in fantasy football, scoring at least 22.7 points (PPR) in each of his first two games this year. There's minimal competition for the 29-year-old in San Francisco, keeping him in the mid-range RB1 tier ahead of Week 3 versus the Arizona Cardinals.

Sunday, September 14, 10:00 PM

Detroit Lions wide receiver Jameson Williams recorded 108 receiving yards in his team's 52-21 Week 2 victory over the Chicago Bears, including a 44-yard touchdown catch. However, Williams hauled in just two passes on four targets, raising questions about whether his role will be expanded beyond being a downfield threat in 2025. The 24-year-old Williams is unquestionably explosive with the ball in his hands, averaging over 17 yards per reception for his career. Still, he's recorded just six catches on nine targets through the first two games of the season after averaging under four catches per game in 2024. Williams profiles as a boom/bust fantasy WR3/flex option until proven otherwise.