Who Should I Start? Elijah Mitchell or Isaac Guerendo

Friday, September 5, 7:20 PM

Kansas City Chiefs running back Elijah Mitchell is a healthy inactive for the Week 1 regular-season opener on Friday night in Brazil against the division-rival Los Angeles Chargers, according to Nate Taylor of ESPN. It's bad news for Mitchell heading into his first year with the Chiefs, as it looks like he's the RB4 to open the year, behind starter Isiah Pacheco, Kareem Hunt and rookie Brashard Smith. The 27-year-old was getting some first-team reps early in training camp, but that was a long time ago in late July. Mitchell signed a one-year, $2.5 million deal with KC in the offseason after spending his first three NFL seasons with the San Francisco 49ers. In his three years in the Bay Area, the former sixth-rounder in 2021 out of Louisiana averaged 4.7 yards per tote on 327 rush attempts for 1,523 yards and nine touchdowns (five in his rookie season).

Saturday, September 6, 6:51 AM

Second-year running back Isaac Guerendo opens the season third on the 49ers' depth chart, though he may already see more action than originally anticipated. Christian McCaffrey (calf) popped up on the team's injury report this week and is tagged as questionable for San Francisco's Week 1 matchup against the Seahawks. Guerendo's only route to fantasy relevance relies on CMC sitting. If that does happen, then he can be seen as a deep-league flex candidate. Brian Robinson Jr. will likely draw the start, but Guerendo made his mark in 2024 in similar circumstances and is a potential RB4/5 pending McCaffrey's status.