Who Should I Start? Emari Demercado or Isaac Guerendo

Sunday, October 5, 12:26 PM

ESPN's Adam Schefter reports that Arizona Cardinals running back Emari Demercado "will stay in the same role" on third downs. Meanwhile, Michael Carter will take over on first and second downs with Trey Benson (knee) out four to six weeks after having surgery on his meniscus. James Conner (ankle) has already been lost for the year, so the Cardinals' backfield depth is being tested early on. Arizona could plan more designed runs for slippery quarterback Kyler Murray, too. Demercado had two carries for eight yards and caught both of his targets for 13 yards and a touchdown in the Week 4 loss to the Seattle Seahawks. While the 26-year-old will be more involved with Benson out, it's Carter that should see more volume, and thus be a better flex play in fantasy lineups, starting this Sunday against the winless Tennessee Titans. Demercado is a better flex option in PPR formats.

Saturday, September 27, 5:08 AM

San Francisco 49ers running back Isaac Guerendo has yet to see an offensive snap in 2025, and there is little reason to expect that to change in Week 4. Christian McCaffrey is the team's unquestioned starter, and Brian Robinson Jr. has the second position on the depth chart locked down. The team's official depth chart lists both Guerendo and rookie Jordan James as the third-string running back, raising the question of which of the two would be given an opportunity in the backfield should the need arise. In the meantime, Guerendo has been relegated to kick return duty. Through three games, he has taken back four kicks for a grand total of 82 yards. Until an injury shakes up the depth chart, Guerendo has no place on fantasy football rosters.