Who Should I Start? Jacoby Brissett or Kyler Murray

Saturday, November 15, 10:31 AM

Arizona Cardinals quarterback Jacoby Brissett has been a reliable fantasy option in every game he has started so far, and he will look to maintain his success during Sunday's Week 11 contest against the San Francisco 49ers. In four starts with Kyler Murray (foot) sidelined, Brissett has totaled 1,118 passing yards, eight passing touchdowns, one rushing touchdown, one interception, and three lost fumbles. During that span, he ranks as the overall QB9 in fantasy points per game. The veteran signal-caller handled a very tough test last week against the Seahawks, and so he remains an intriguing fantasy option this week in a slightly softer matchup against the Niners. San Francisco has allowed the eighth-most fantasy points and sixth-most touchdowns to opposing quarterbacks in 2025. The 49ers' defense has also forced just one interception, which is the second-fewest in the NFL. Brissett is a low-end QB1 who can be started in most leagues this week.

Saturday, November 8, 10:56 AM

Arizona Cardinals quarterback Kyler Murray (foot) could be traded or released next offseason as his future with the team is in limbo, according to Adam Schefter of ESPN. Murray maintained a 68.1 percent completion rate with 962 passing yards, 173 rushing yards, seven total touchdowns, and four turnovers through the first five games this season. He then missed three games due to injury, and his absence was extended even further this week as Arizona placed him on injured reserve. Although Murray is sidelined due to injury, there has been some speculation about whether he would have still been benched for Jacoby Brissett even if healthy. Regardless of the behind-the-scenes details, Schefter's report paints a clear picture of a potential separation between the Cardinals and their former No. 1 overall selection. Arizona must make a decision on his future by the fifth day of the 2026 league year next March, when an additional $19.5 million becomes guaranteed. The team's options are to release him, keep him, or try to find a trade partner that is willing to take on the final two years of his expensive contract. One source told Schefter that "separation is imminent" between the two parties, but there's still plenty of time for that sentiment to change between now and March. In the meantime, it'll be Brissett under center for the Cardinals.