Who Should I Start? Joe Mixon or Alvin Kamara

Wednesday, January 21, 12:19 PM

Houston Texans general manager Nick Caserio said on Wednesday that running back Joe Mixon (foot, ankle) had a medical condition that never improved, according to Jonathan M. Alexander of the Houston Chronicle. "He didn't jump off a building. He wasn't doing anything irresponsible. It was a freak thing," Caserio said. The Texans were extremely vague with Mixon's injury all year, and he never ended up playing in 2025. Head coach DeMeco Ryans said on Monday that Mixon's status for the 2026 season is also uncertain due to his injury. Unexpectedly, the Texans struggled for consistent production out of their backfield with a mix of veteran Nick Chubb and Woody Marks. Marks took over halfway through the year and should be heavily involved again next season, even if Mixon returns. Needless to say, a lot of fantasy managers won't want anything to do with Mixon in 2026.

Friday, January 2, 3:42 PM

New Orleans Saints running back Alvin Kamara (knee, ankle) has been ruled out for his team's Week 18 matchup against the Atlanta Falcons, per ESPN's Katherine Terrell. Kamara suffered a sprained MCL in Week 12 that will ultimately end up causing him to miss New Orleans' final six games of the season. Across 11 contests in 2025, the 30-year-old recorded 657 scrimmage yards and one touchdown on 164 touches. His 3.6 yards per carry and 4.0 yards per touch both represent career lows. With Kamara sidelined and Saints backs Kendre Miller (knee) and Devin Neal (hamstring) on Injured Reserve, New Orleans will likely split backfield work between Audric Estime and Evan Hull in Week 18, with tight end Taysom Hill possibly mixing in as well. Estime functioned as the team's lead back in Week 17, recording 14 carries for 94 yards and a touchdown against the Tennessee Titans.