Who Should I Start? Joe Mixon or CeeDee Lamb

Thursday, November 20, 12:34 PM

Houston Texans running back Joe Mixon (ankle, foot) is not expected to play this season as he deals with a foot injury from the offseason, according to Ian Rapoport of NFL Network. Mixon will likely stay on the Physically Unable to Perform list through the end of the 2025 season, while the Texans move forward with veteran Nick Chubb and rookie Woody Marks in their backfield. Things had been trending this way for a while, as the Texans haven't been giving any real updates on Mixon for pretty much the entire season. Fantasy managers who are still stashing the 29-year-old in redraft leagues should send him to the waiver wire now. Mixon's injury dates all the way back to spring workouts. One would think he'd be ready for the start of the 2026 campaign, but there has been little information about the exact nature of his injury. Marks, a fourth-rounder in April, has slowly started to see more work and should be the backfield leader over Chubb by the end of the year.

Saturday, November 22, 2:50 PM

Across seven games in 2025, Dallas Cowboys wide receiver CeeDee Lamb has recorded 40 catches for 557 yards and two touchdowns on 61 targets. Even with fellow Dallas wideout George Pickens in the midst of a breakout season, Lamb has earned double-digit targets in four out of the six games where he has played all four quarters. In Week 12, Lamb gets a difficult matchup when the Cowboys host the Philadelphia Eagles. For the season, the Eagles are tied with the Denver Broncos and Kansas City Chiefs for the fewest passing touchdowns allowed (nine). Philadelphia has also played some of its best defense of late, holding the Green Bay Packers and Detroit Lions to a combined 16 points over the last two weeks. Still, in his first matchup of the season against the Eagles in Week 1, Lamb recorded seven catches for 110 yards on 13 targets and could have had an even bigger game if not for a couple of uncharacteristic drops. He remains a clear must-start fantasy wide receiver in Week 12 against his division rival.