Who Should I Start? Joe Mixon or Darius Slayton


Week 5 Projections

Fant.
Pts.
Rush.
Yds.
Rush
TD
Rec. Rec.
Yds.
Rec
TD
0.0 0.0 0.0 0.0 0.0 0.0

Joe Mixon News

Joe Mixon Dealing With Degenerative Foot Injury

Tuesday, October 6, 4:01 PM

Reports circulated on Monday that the Seattle Seahawks were on the verge of signing veteran free-agent running back Joe Mixon (foot) to their roster in the wake of placing rookie first-round RB Jadarian Price (chest) on Injured Reserve over the weekend. However, the Seahawks elected not to sign Mixon to their practice squad in the end thanks to a troublesome foot issue that caused him to miss the entire 2025 season while with the Houston Texans, according to Ian Rapoport of the NFL Network. Mixon is specifically dealing with a degenerative foot issue that could wind up putting a premature end to his NFL career. There are other RB-needy teams around the NFL, specifically the Philadelphia Eagles, but it is "up for debate" whether Mixon will actually sign with another team or play another down in an NFL game. Until Zach Charbonnet (knee) can make his 2026 season debut, the Seahawks will move forward with Emanuel Wilson and George Holani sharing touches in the backfield. Mixon, a former second-rounder by the Cincinnati Bengals in 2017, is a two-time Pro Bowler and reached the 1,000-yard rushing mark in five of his eight NFL seasons.


Week 5 Projections

Fant.
Pts.
Rush.
Yds.
Rush
TD
Rec. Rec.
Yds.
Rec
TD
0.0 0.0 0.0 0.0 0.0 0.0

Darius Slayton News

Darius Slayton Won't Play for Colts in Week 5

Saturday, October 10, 8:06 AM

The Indianapolis Colts downgraded wide receiver Darius Slayton (knee) from questionable to out for their Week 5 contest on Sunday at the Pittsburgh Steelers. Slayton is dealing with a new knee injury, but he was able to practice on a limited basis on Friday. His next chance to make his Colts debut will come in Week 6 against the division-rival Tennessee Titans. Alec Pierce (heel) is on Injured Reserve, and veteran Keenan Allen (groin) is questionable to play this weekend, so Indy's receiving corps is thinned out behind Josh Downs. Laquon Treadwell and Deion Burks are the next men up in the Steel City in Week 5, so quarterback Daniel Jones will not be much of an upside play as a QB2 in two-QB superflex leagues against the Steelers. After being cut by the New York Giants, Slayton signed with the Colts on Sept. 21, but he has yet to play in a game with the team. The 29-year-old caught 37 passes for 538 yards and only one touchdown in 14 games in 2025 in his final season with the G-Men. The Colts' lack of WR depth is one of the reasons they have been mentioned as a potential suitor for Arizona Cardinals receiver Marvin Harrison Jr.


Joe Mixon vs. Darius Slayton

Still trying to decide between Mixon and Slayton? Check on the latest news to make sure both players are active and healthy. Our PPR projections show that Joe Mixon is projected to score 0.0 points this week while Darius Slayton is projected to score 0.0 points.