Who Should I Start? Joe Mixon or Najee Harris

Thursday, November 20, 12:34 PM

Houston Texans running back Joe Mixon (ankle, foot) is not expected to play this season as he deals with a foot injury from the offseason, according to Ian Rapoport of NFL Network. Mixon will likely stay on the Physically Unable to Perform list through the end of the 2025 season, while the Texans move forward with veteran Nick Chubb and rookie Woody Marks in their backfield. Things had been trending this way for a while, as the Texans haven't been giving any real updates on Mixon for pretty much the entire season. Fantasy managers who are still stashing the 29-year-old in redraft leagues should send him to the waiver wire now. Mixon's injury dates all the way back to spring workouts. One would think he'd be ready for the start of the 2026 campaign, but there has been little information about the exact nature of his injury. Marks, a fourth-rounder in April, has slowly started to see more work and should be the backfield leader over Chubb by the end of the year.

Wednesday, September 24, 6:15 PM

The Los Angeles Chargers announced on Wednesday that they placed running back Najee Harris (Achilles) on Injured Reserve, according to Fernando Ramirez of the Sporting Tribune. Harris' season is over after he tore his Achilles in the Week 3 win over the Denver Broncos on Sunday. It's a disappointing end to his first year with the Bolts after signing with them in free agency in the offseason. The 27-year-old will end his streak of four straight 1,000-yard rushing seasons to begin his career. In his three games this year, Harris carried the ball 15 times for 61 yards and no touchdowns, adding three receptions for 25 yards through the air. The Chargers will be forced to lean more on rookie first-rounder Omarion Hampton as their lead back going forward, making him a must-start each week. Hassan Haskins will be elevated to the RB2 role, with Kimani Vidal the next man up at No. 2 in the backfield.