Who Should I Start? Kyren Williams or Isaac Guerendo

Sunday, November 2, 10:32 PM

Los Angeles Rams running back Kyren Williams wasn't involved in the passing game at all on Sunday, but he was efficient on the ground in the team's 34-10 victory over the visiting New Orleans Saints in Week 9. Williams had some nice volume in this one, handling a season-high 25 carries for a season-high 113 rushing yards and his third rushing touchdown of the year. It was the 25-year-old's first 100-yard rushing game in 2025. Williams hasn't been all that explosive on the ground for the Rams this year, but it was nice to finally see him top the century mark in a plus matchup with a positive game script all day. The former fifth-rounder has been more of an RB2 for fantasy managers this year in a Rams offense that prefers to air it out with the arm of quarterback Matthew Stafford. Still, Williams should be considered a must-start in a big Week 10 divisional contest next Sunday versus a banged-up San Francisco 49ers defense.

Tuesday, October 21, 9:16 PM

San Francisco 49ers running back Isaac Guerendo was thrust into action in his rookie season in the NFL in 2024 because Christian McCaffrey missed most of the year due to injuries. Guerendo finished with 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) and also chipped in 15 catches on 16 targets as a pass-catcher for 152 yards. Fantasy managers probably viewed him as a pretty valuable handcuff for the injury-prone CMC going into 2025 drafts, but the Niners' acquisition of Brian Robinson Jr. before the season pretty much killed whatever fantasy appeal he had. Through the first seven weeks of his sophomore campaign, the 25-year-old former fourth-rounder has yet to play an offensive snap with CMC and B-Rob both staying healthy. Instead, Guerendo has been limited to a special teams role, returning five kickoffs for a combined 100 yards.