Who Should I Start? Kyren Williams or Isaac Guerendo

Thursday, December 18, 1:36 AM

Los Angeles Rams running back Kyren Williams has been terrific lately, and he'll look to extend his bout of success (as well as his three-game touchdown streak) during Thursday's Week 16 contest against the Seattle Seahawks. The Rams have made a significant effort to reduce Williams' workload so that he stays fresh for the playoffs, but even so, he has continued to operate as a mid-to-low RB1 in fantasy football. Over his last three games, he has 234 rushing yards, 23 receiving yards, and four total touchdowns. He owns a phenomenal average of 5.7 yards per carry during that span, and he's the overall RB9 in PPR leagues through 14 games this season. If Williams keeps up this pace, he'll be a top-10 fantasy running back for the third consecutive year. The 25-year-old's ability to produce on a slightly reduced workload has been terrific for fantasy managers, and that trend should continue in Week 16. While the Seahawks have allowed the third-fewest fantasy points to running backs in 2025, Williams has shown that he is matchup-proof. In fact, when he faced the Seahawks just five weeks ago, he had 91 rushing yards and a touchdown. He ranks as the overall RB16 in RotoBaller's latest fantasy rankings, but there's no doubt that he has top-12 upside. He should be started in all leagues ahead of Thursday Night Football in Week 16.

Tuesday, October 21, 9:16 PM

San Francisco 49ers running back Isaac Guerendo was thrust into action in his rookie season in the NFL in 2024 because Christian McCaffrey missed most of the year due to injuries. Guerendo finished with 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) and also chipped in 15 catches on 16 targets as a pass-catcher for 152 yards. Fantasy managers probably viewed him as a pretty valuable handcuff for the injury-prone CMC going into 2025 drafts, but the Niners' acquisition of Brian Robinson Jr. before the season pretty much killed whatever fantasy appeal he had. Through the first seven weeks of his sophomore campaign, the 25-year-old former fourth-rounder has yet to play an offensive snap with CMC and B-Rob both staying healthy. Instead, Guerendo has been limited to a special teams role, returning five kickoffs for a combined 100 yards.