Who Should I Start? Miles Sanders or Dylan Sampson

Friday, October 10, 5:02 PM

Dallas Cowboys running back Miles Sanders (ankle, knee) has been moved to season-ending injured reserve, according to Patrick Walker of the Dallas Cowboys. Sanders was limited in practice on Wednesday before missing Thursday's practice, but now his season is over as he deals with multiple injuries to his ankle and knee. The 28-year-old served as the primary backup running back to Javonte Williams over the first four games of the season before missing Week 5. Rookie Jaydon Blue was active in his place and should step into a larger role now with Sanders out. Blue shouldn't be in lineups for Week 6, but he is an interesting speculative pickup ahead of Sunday's game against the Panthers.

Saturday, January 3, 12:12 PM

Cleveland Browns running back Dylan Sampson returned from calf and hand injuries that sidelined him for two games in Week 17 and recorded 27 yards from scrimmage on 14 touches against the Pittsburgh Steelers. With Browns running back Quinshon Judkins (leg, ankle) on Injured Reserve, Sampson should have a chance to lead his team's backfield once again in Week 18 against the Cincinnati Bengals. Cincinnati has been one of the NFL's worst rush defenses in 2025, ranking 30th in the league in yards per carry allowed (5.2) and 32nd in runs of 20 or more yards allowed (19). Sampson will likely split touches with Browns backs Raheim Sanders and Trayveon Williams in Week 18, which limits his ceiling. However, Sampson has recorded 10 receptions for 123 yards and a touchdown on 12 targets across his last four games, which provides a relatively safe PPR floor. Fantasy managers should view Sampson as a low-end flex option in Week 18 against Cincinnati.