Who Should I Start? Ray Davis or Isaac Guerendo

Saturday, October 25, 2:11 PM

Buffalo Bills running back Ray Davis hauled in two receptions, including a touchdown against the Falcons in Week 6. Despite his season-high production, Davis remains strictly a handcuff for James Cook, as he has seen less than three touches in every game outside of the team's Week 2 blowout of the Jets. Davis accounts for just 7% of the team's rushing attempts this season, and has been targeted just four times in the passing game. Expect to see a hard-fought matchup with a stingy Panthers defense that will likely keep the Bills starters on the field throughout the game, making Davis nothing more than a handcuff for Cook.

Tuesday, October 21, 9:16 PM

San Francisco 49ers running back Isaac Guerendo was thrust into action in his rookie season in the NFL in 2024 because Christian McCaffrey missed most of the year due to injuries. Guerendo finished with 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) and also chipped in 15 catches on 16 targets as a pass-catcher for 152 yards. Fantasy managers probably viewed him as a pretty valuable handcuff for the injury-prone CMC going into 2025 drafts, but the Niners' acquisition of Brian Robinson Jr. before the season pretty much killed whatever fantasy appeal he had. Through the first seven weeks of his sophomore campaign, the 25-year-old former fourth-rounder has yet to play an offensive snap with CMC and B-Rob both staying healthy. Instead, Guerendo has been limited to a special teams role, returning five kickoffs for a combined 100 yards.