Who Should I Start? Travis Etienne Jr. or Omarion Hampton

Sunday, September 28, 9:38 PM

Jacksonville Jaguars running back Travis Etienne Jr. dominated the San Francisco 49ers with 19 carries for 124 yards and a touchdown in his team's 26-21 Week 4 win. The 26-year-old is off to a terrific start to the 2025 season, with 65 carries for 394 yards and two touchdowns as a rusher, and six catches for 32 yards and a score as a receiver through his first four games. Etienne Jr. is also dominating backfield touches in Jacksonville so far, as Jaguars backup running backs Bhayshul Tuten and LeQuint Allen Jr. combined for just six touches in Week 4. Etienne Jr. profiles as a must-start fantasy running back going into a Week 5 showdown with the Kansas City Chiefs.

Sunday, October 12, 9:16 AM

Los Angeles Chargers running back Omarion Hampton (ankle) is expected to spend more than the minimum four weeks on injured reserve, according to Mike Garafolo of NFL Network. The injury that the rookie suffered in Week 5 appears to be serious enough that he'll be out through at least Week 10, and perhaps longer. The Chargers have a Week 12 bye, so it wouldn't be surprising to see Los Angeles hold him out until Week 13, giving him an extra week off to rest. Losing both Hampton and Najee Harris (Achilles) is a major blow for the Chargers, who will turn to Hassan Haskins and Kimani Vidal but could also look to make external running back additions.