Who Should I Start? Trey Benson or Isaac Guerendo

Friday, December 5, 11:14 PM

Arizona Cardinals running back Trey Benson (knee) has been sidelined since Week 4 after suffering a knee injury and being placed on Injured Reserve. Benson was a non-participant every day in practice this week, marking five missed sessions in a row, and was officially ruled out for Week 14 against the Los Angeles Rams. The second-year back hasn't practiced since last Wednesday, and time is running out for him to return this season. The Florida State product was in line for a workhorse role after James Conner (foot) went down for the season in Week 3, but Benson's opportunity has been derailed by a nagging knee injury that required surgery. He played well in the four games he suited up for this year, recording 29 carries for 160 yards while adding 13 receptions (16 targets) for 64 yards. Benson is still a good stash, as he would be the Cardinals' lead back if he returns, but that's still an unknown as of now. Arizona will continue to rely on the combination of Bam Knight and Michael Carter in Week 14.

Tuesday, October 21, 9:16 PM

San Francisco 49ers running back Isaac Guerendo was thrust into action in his rookie season in the NFL in 2024 because Christian McCaffrey missed most of the year due to injuries. Guerendo finished with 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) and also chipped in 15 catches on 16 targets as a pass-catcher for 152 yards. Fantasy managers probably viewed him as a pretty valuable handcuff for the injury-prone CMC going into 2025 drafts, but the Niners' acquisition of Brian Robinson Jr. before the season pretty much killed whatever fantasy appeal he had. Through the first seven weeks of his sophomore campaign, the 25-year-old former fourth-rounder has yet to play an offensive snap with CMC and B-Rob both staying healthy. Instead, Guerendo has been limited to a special teams role, returning five kickoffs for a combined 100 yards.