These are the top fantasy football players of the Indianapolis Colts as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of October 17, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|
| Week | Home/Away | Opponent |
|---|---|---|
| 10 | Home | Atlanta Falcons |
| 1 | Home | Miami Dolphins |
| 2 | Home | Denver Broncos |
| 3 | Away | Tennessee Titans |
| 4 | Away | Los Angeles Rams |
| 5 | Home | Las Vegas Raiders |
| 6 | Home | Arizona Cardinals |
| 7 | Away | Los Angeles Chargers |
| 8 | Home | Tennessee Titans |
| 9 | Away | Pittsburgh Steelers |
| 12 | Away | Kansas City Chiefs |
| 13 | Home | Houston Texans |
| 14 | Away | Jacksonville Jaguars |
| 15 | Away | Seattle Seahawks |
| 16 | Home | San Francisco 49ers |
| 17 | Home | Jacksonville Jaguars |
| 18 | Away | Houston Texans |
Indianapolis Colts tight end Tyler Warren turned in another strong performance in a Week 6 win over the Arizona Cardinals, catching six of his nine targets for 63 yards and a touchdown. With 29 catches for 370 yards and three all-purpose touchdowns through six games, Warren has cemented himself as a no-brainer top-six tight end in fantasy for the remainder of the season. He will look to keep it going in a Week 7 road matchup against the Los Angeles Chargers. The Chargers have been tough on tight ends in fantasy this season, allowing just the 26th-most fantasy points per game to the position through six games. That being said, Warren has been too dominant to treat as anything other than a top-three fantasy option at his position for Week 7.
October 17, 2025 8:45 PM EST
Indianapolis Colts wide receiver Adonai Mitchell will be active in Week 7 against the Los Angeles Chargers after he was inactive in Week 6 and played just six snaps in Week 5. The Colts effectively benched Mitchell after he made several mistakes in a Week 4 loss to the Los Angeles Rams, but they will turn back to him with both Josh Downs (concussion) and Ashton Dulin (chest) inactive for Week 7. The Chargers represent a tough matchup for Mitchell as they are allowing just the 30th-most fantasy points per game to receivers this season. It also remains to be seen just how much the Colts use Mitchell in Week 7, even with him active. He should not be in fantasy lineups against the Chargers this weekend.
October 17, 2025 8:37 PM EST
Indianapolis Colts wide receiver Alec Pierce (ankle) returned from a two-game absence to catch two passes for 48 yards in a 31-27 win over the Arizona Cardinals in Week 6. Pierce was listed with an ankle injury this week, but he practiced fully on Wednesday, Thursday, and Friday, and is good to go for a road matchup against the Los Angeles Chargers in Week 7. Pierce could see a larger role with Josh Downs (concussion) ruled out after suffering a concussion. While he is not a safe play, Pierce sets up as a boom/bust flex option who is worth a look in deeper leagues in Week 7.
October 17, 2025 8:32 PM EST
Indianapolis Colts wide receiver Michael Pittman Jr. turned in a slow day at the office in a 31-27 win over the Arizona Cardinals in Week 6, catching just two of his three targets for 20 yards as the team leaned on Josh Downs (concussion) in the passing attack. Pittman has a chance to bounce back on the road in Week 7 against the Los Angeles Chargers as Downs has been ruled out with a concussion. The Chargers have been excellent against receivers in fantasy this season as they are allowing just the 30th-most fantasy points per game to the position through six games. With four touchdowns already in six games, Pittman is safe to deploy as a low-end WR2 in fantasy in Week 7 despite the difficult matchup.
Michael Pittman Jr. player page.
October 17, 2025 8:25 PM EST
Indianapolis Colts running back DJ Giddens was quiet in a Week 6 win over the Arizona Cardinals as he did not receive a touch while playing just two snaps on offense. The Colts surprisingly turned to Ameer Abdullah in the game as he notched two touches behind workhorse Jonathan Taylor. Giddens will look to get back in the stat sheet in a Week 7 road matchup against the Los Angeles Chargers. The Colts are one of the few teams that lean heavily on just one running back in Taylor, which doesn't leave much work for his backups. That being said, Giddens is still worth keeping an eye on as a handcuff option in case Taylor is forced to miss time at any point, although that could change if he plays behind Abdullah again in Week 7.
October 17, 2025 8:21 PM EST
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