Demaryius Thomas DEN vs New England
New England's defense has improved greatly after their disastrous start to the season, but they are still fantasy's second worst defense against opposing wide receivers on the season (and the only team worse is on a bye). Demaryius Thomas loves to play the Patriots, averaging just under 100 yards on 11+ targets per game in six career matchups with New England. He showed good chemistry with Brock Osweiler last week and should be a strong play even as Denver struggles. Emmanuel Sanders is ranked just inside the top 30 and also has a good history against the Patriots, so he looks like a good play too if healthy.
Robby Anderson NYJ vs Tampa Bay
Robby Anderson has emerged as the clear WR1 for the Jets. He's been first or second on the team in targets every game of the season, though he has struggled to convert all those targets into a high number of receptions. A game against this Bucs secondary should be just what the doctor ordered. Tampa Bay has allowed 117 receptions to opposing wide receivers, second most of any team, and the third most fantasy WR points. Anderson has been a low-upside flex play most of the season, but he looks like a must start this week.
Robert Woods LAR vs Houston
It turns out that Robert Woods, not Sammy Watkins or Cooper Kupp, has become the go to Rams receiver. He's had at least five targets in all but one game for Los Angeles and leads the team in receptions, and now he broke out with a pair of touchdowns last week too. The Rams offense continues to be scorching hot and now they'll face a Texans defense ravaged by injuries, so Woods has a chance to put up another big game. He's had double digit points in PPR leagues in four straight games.
Adam Humphries TB vs New York Jets
Mike Evans has been suspended, so it's up to DeSean Jackson and Adam Humphries at receiver this week. Jackson has a higher upside because he can always catch a long one, but Humphries seems like the better bet to lead the team in targets and receptions. He's played almost as many snaps as Jackson as the third receiver and should see seven to ten targets and hit double digits easily in PPR leagues. The Jets are among the five worst pass defenses this season against receivers. Humphries is this week's waiver wire plug and play if you're short on options.
Marquise Goodwin SF vs New York Giants
The Giants bottom ten pass defense is ripe for the picking, but we'll see if anyone from San Francisco is up to the task. It looks like C.J. Beathard will be under center again, which makes sense with the 49ers heading into a bye week where they can turn the offense over to Jimmy Garoppolo. That bodes well for Marquise Goodwin, who led all 49ers receivers in snaps last week with Pierre Garcon headed to the IR. Goodwin averaged seven targets a week in October, and he's always a threat to bust a long one with his blazing speed. He's a high upside lottery ticket.