Who Should I Start? Alvin Kamara or Isaac Guerendo

Friday, November 7, 4:06 PM

New Orleans Saints running back Alvin Kamara (ankle) is officially listed as questionable headed into Sunday's matchup against the Carolina Panthers, according to Katherine Terrell of ESPN. Kamara was a limited participant in every day of practice this week, but he followed a similar pattern last week and was able to play in Week 9 against the Rams. The veteran back has been managing this ankle injury for five weeks now, but hasn't missed any games and should be ready to go in Week 10. However, the lingering ankle issue has likely contributed to his poor production this season, averaging a career-low 3.6 yards per carry and scoring only one touchdown. Some of that can be attributed to New Orleans' poor offensive environment, but it's been a disappointing year regardless for the 30-year-old. Kamara profiles as an RB3/flex option for Week 10 against the Panthers.

Tuesday, October 21, 9:16 PM

San Francisco 49ers running back Isaac Guerendo was thrust into action in his rookie season in the NFL in 2024 because Christian McCaffrey missed most of the year due to injuries. Guerendo finished with 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) and also chipped in 15 catches on 16 targets as a pass-catcher for 152 yards. Fantasy managers probably viewed him as a pretty valuable handcuff for the injury-prone CMC going into 2025 drafts, but the Niners' acquisition of Brian Robinson Jr. before the season pretty much killed whatever fantasy appeal he had. Through the first seven weeks of his sophomore campaign, the 25-year-old former fourth-rounder has yet to play an offensive snap with CMC and B-Rob both staying healthy. Instead, Guerendo has been limited to a special teams role, returning five kickoffs for a combined 100 yards.