Who Should I Start? Amon-Ra St. Brown or Brian Thomas Jr.

Friday, September 26, 10:50 PM

Detroit Lions wide receiver Amon-Ra St. Brown is off to a stellar start to the 2025 season, recording 20 catches for 237 yards and four touchdowns through his first three games. St. Brown has been targeted a team-high 25 times and is the clear number one option in Detroit's passing game. The Lions offense has a difficult matchup in Week 4 against the Cleveland Browns, who have allowed the fifth-fewest passing yards (521) in the NFL so far. However, St. Brown is a receiver who can win in the short and intermediate areas, so he could still see a high target volume even in the Lions' struggle to push the ball downfield. St. Brown is a must-start fantasy wide receiver in Week 4.

Saturday, September 27, 8:31 PM

Jacksonville Jaguars wide receiver Brian Thomas Jr. (wrist) doesn't carry an injury designation ahead of the Week 4 matchup with the 49ers. Thomas has been battling a wrist injury. Fortunately, he logged full practices throughout the week. Thomas had a stellar rookie year, amassing 87 catches (133 targets) for 1,282 yards and 10 touchdowns. However, he struggled in the Jags' first three games of the 2025 campaign, catching only seven passes for 115 yards. With that in mind, Thomas has been targeted 25 times this season, so it's obvious he remains a go-to option for quarterback Trevor Lawrence. While the 22-year-old still can't be trusted fully from a fantasy standpoint, there's really not a scenario where managers can feel comfortable keeping him out of the starting lineup, especially considering his upside. It's also worth noting that Dyami Brown (shoulder) may not play.