Who Should I Start? Brandon Aiyuk or Joshua Palmer

Wednesday, November 26, 3:44 PM

The San Francisco 49ers will not open the 21-day practice window for wide receiver Brandon Aiyuk (knee) this week, according to head coach Kyle Shanahan. The same goes for fellow wideout Jacob Cowing (hamstring). A report surfaced last week that the 49ers voided guarantees in Aiyuk's four-year contract extension, which could lead to the 27-year-old former first-rounder sitting out the entire 2025 campaign. If that happens, the 49ers would likely release him at season's end. Fantasy managers who have been stashing Aiyuk all season long might not get to use him at all. It's good news for the rest-of-season outlooks for both Jauan Jennings and Ricky Pearsall, as well as tight end George Kittle. Aiyuk has been recovering from his season-ending injury last year, in which he tore both his ACL and MCL.

Wednesday, November 26, 9:27 PM

Buffalo Bills wide receiver Joshua Palmer (ankle) was a limited participant during Wednesday's practice session. Palmer was a bit banged up heading into last Thursday's game versus the Houston Texans. Despite that, Palmer suited up and hauled in two of his four targets for 21 yards in the loss. It appears Palmer is still dealing with an ankle issue right now. Barring any setbacks, Palmer should be ready to go for the Week 13 matchup against the Pittsburgh Steelers. The 26-year-old isn't an ideal fantasy option when healthy anyway.