Who Should I Start? Brandon Aiyuk or Joshua Palmer

Wednesday, November 5, 6:04 PM

San Francisco 49ers head coach Kyle Shanahan said on Wednesday that he's "pretty confident" that wide receiver Brandon Aiyuk (knee) will play at some point this season, according to David Lombardi of The San Francisco Standard. However, the 49ers are still waiting for Aiyuk to "hit certain markers" on GPS speed measurements before opening his 21-day practice window. Once Aiyuk returns to practice, the team will have 21 days to officially activate him from the Physically Unable to Perform list. Despite the optimism, reports on Monday suggested that the 27-year-old former first-rounder wasn't close to a return to practice, so fantasy managers who have been stashing Aiyuk all year shouldn't get their hopes up. Aiyuk suffered a torn ACL and MCL in Week 7 of last year and probably won't be back in games for the 49ers until December.

Friday, November 7, 12:06 PM

Buffalo Bills head coach Sean McDermott said that wide receiver Joshua Palmer (ankle, knee) is questionable to play in Week 10 against the division-rival Miami Dolphins on Sunday, according to Joe Buscaglia of The Athletic. Palmer has been limited in practice all week and is up in the air to make his return this weekend. The 26-year-old hasn't played since Week 6, so even if he gets the green light to suit up this Sunday, he won't be guaranteed significant snaps on offense as WR depth behind Khalil Shakir and Keon Coleman. Palmer hasn't made much of a fantasy impact in his first year in Buffalo to begin with, catching 14 passes for 234 yards and no touchdowns in six games played. Shakir is really the only wideout in Buffalo that is worth weekly starting consideration through nine weeks in 2025.