Who Should I Start? Brandon Aiyuk or Keon Coleman

Tuesday, August 26, 5:06 PM

The San Francisco 49ers officially placed wide receiver Brandon Aiyuk (knee) on the Reserve/Physically Unable to Perform list to begin the 2025 season, which means he will miss at least the first four contests. Head coach Kyle Shanahan has already said that Aiyuk might be targeting a return around Week 6 on the road against the Tampa Bay Buccaneers. The 27-year-old suffered a torn ACL and MCL in Week 7 of last season, which is why he's not ready for the start of 2025. The former first-round wideout had been a major disappointment in fantasy before his season-ending knee injury, too, as he caught just 25 of 47 targets for 374 yards and didn't find the end zone once in seven games. It's understandable for fantasy managers to want to avoid him altogether this year, although he's still worth drafting in leagues with IR spots. With Aiyuk sidelined, Jauan Jennings (calf) and Ricky Pearsall should serve as the top wideouts in San Fran.

Wednesday, September 3, 5:15 PM

Buffalo Bills wide receiver Keon Coleman (groin) was listed as limited in the team's first official practice on Wedneday heading into a Week 1 showdown on Sunday night against the Baltimore Ravens. Coleman should be good to go for Sunday evening's tilt, but he'll have two more days to get in a full practice. Fellow wideout Khalil Shakir (ankle) practiced in full, so quarterback Josh Allen should have his top two receivers available. Coleman, who was a second-rounder last year out of Florida State, played in only 13 games in the regular season in his rookie year due to injuries and finished with a 29-556-4 line. He was inconsistent, but he has showns signs this summer of taking on an elevated role in Year 2. Still, with Joshua Palmer now in the fold in an offense that spreads the ball around, Coleman should be considered a WR4/flex for fantasy against Baltimore in Week 1.