Who Should I Start? Brandon Aiyuk or Keon Coleman

Wednesday, November 5, 6:04 PM

San Francisco 49ers head coach Kyle Shanahan said on Wednesday that he's "pretty confident" that wide receiver Brandon Aiyuk (knee) will play at some point this season, according to David Lombardi of The San Francisco Standard. However, the 49ers are still waiting for Aiyuk to "hit certain markers" on GPS speed measurements before opening his 21-day practice window. Once Aiyuk returns to practice, the team will have 21 days to officially activate him from the Physically Unable to Perform list. Despite the optimism, reports on Monday suggested that the 27-year-old former first-rounder wasn't close to a return to practice, so fantasy managers who have been stashing Aiyuk all year shouldn't get their hopes up. Aiyuk suffered a torn ACL and MCL in Week 7 of last year and probably won't be back in games for the 49ers until December.

Saturday, November 8, 12:54 AM

Buffalo Bills wide receiver Keon Coleman has seen his targets diminished as the offense continues to focus on Khalil Shakir and Dalton Kincaid in the passing game. The Bills' reliance on their running game, first in the NFL with 161.5 yards per game, also factors into Coleman's diminished targets. The second-year receiver saw just two targets last week and hasn't eclipsed 50 yards in a game since Week 1. Coleman should not be started in any format until he can carve out a consistent role in the Bills' explosive offense.