Who Should I Start? Brandon Aiyuk or Keon Coleman

Monday, November 17, 3:31 PM

The San Francisco 49ers won't open the practice windows for either wide receiver Brandon Aiyuk (knee) or Jacob Cowing (hamstring) this week, according to head coach Kyle Shanahan. Aiyuk, who has been out all year since tearing multiple ligaments in his knee in Week 7 of 2024, remains "week-to-week. Cowing, meanwhile, will not have his practice window opened until after the team's Week 14 bye. Aiyuk will not make his season debut in Week 12 versus the Carolina Panthers, and he's probably unlikely to return in Week 13 against the Cleveland Browns, either. Time is running out for the 27-year-old former first-rounder to make an impact for fantasy managers who have been stashing him all year. The Niners have a good matchup coming out of their bye in Week 15 against the Titans, but even if Aiyuk can play in that game, he'd be a very risky option for those playing in the first week of the fantasy playoffs in most leagues.

Sunday, November 16, 12:11 PM

Updating a previous report, Buffalo Bills wide receiver Keon Coleman is inactive on Sunday as a healthy scratch against the Tampa Bay Buccaneers in Week 11 because he missed a team meeting on Friday morning, a source told Adam Schefter of ESPN. Until then, the Bills planned to play him, but their plans changed after Coleman missed the meeting. Buffalo will also be without tight end Dalton Kincaid after he injured his hamstring in last week's upset loss to the Miami Dolphins. The 22-year-old second-year wideout caught his third touchdown of the year in Week 10, but overall, Coleman has been a big disappointment for Buffalo and his fantasy managers in 2025 with 32 total catches for 330 yards and three scores in nine games played. With Coleman now out on Sunday, Khalil Shakir, Joshua Palmer, and Curtis Samuel should be Buffalo's top receivers, with tight end Dawson Knox also seeing a notable boost in target share.