San Francisco 49ers running back Christian McCaffrey (illness) was a full-go in practice on Friday and was removed from the Week 15 injury report, according to Cam Inman of the Bay Area News Group. McCaffrey is fully expected to play on Sunday against the visiting Tennessee Titans after he came down with an illness this week and was limited in practice on Thursday. CMC is an absolute must-start in Week 15 against the Titans, a team that allows 122.5 rushing yards per game. The 29-year-old comes into Week 15 action as the RB2 in half-PPR points on the year, thanks to 849 rushing yards and eight touchdowns on 237 carries. McCaffrey hasn't been that great on the ground, but where he excels is as a pass-catcher, as he leads all backs in catches (85), targets (107), receiving yards (806), and touchdowns (five), and it's not even close.
Dec 12, 2025 7:25 PM EST
San Francisco 49ers running back Christian McCaffrey (illness) was a limited participant during practice on Thursday. This was an improvement in status for McCaffrey, who missed practice entirely on Wednesday. He's trending in the right direction to play against the Tennessee Titans in Week 15, but managers should check back on Friday for additional confirmation on his status. If he's able to practice in full, he could avoid any sort of injury designation heading into the weekend. However, if he remains limited, the 49ers may list him as questionable. With that being said, the fact that McCaffrey was able to get on the field in some capacity on Thursday bodes well for his Week 15 availability. If active, he'll rank as a high-end RB1 against the Titans, who have allowed the 10th-most fantasy points to running backs in 2025.
Dec 11, 2025 8:45 PM EST
San Francisco 49ers running back Christian McCaffrey handled 20 carries for 53 yards and a touchdown in the team's 26-8 win over the Browns in Week 13. He also caught all four of his targets for 21 receiving yards. Sunday's game was just the third time this season that McCaffrey finished with fewer than 100 scrimmage yards, and his four targets were a season low. Still, the two-time All-Pro finished as a top-12 running back in PPR scoring for the twelfth time in 13 weeks. Fantasy football managers will have to do without McCaffrey's services in Week 14 while the 49ers are on bye. Those lucky enough to have sewn up a spot in the fantasy football playoffs get to look forward to a matchup against the Titans in Week 15.
Dec 2, 2025 4:21 PM EST
San Francisco 49ers running back Christian McCaffrey enters Week 13 leading the NFL in touches (298) and second in receptions (81). Amid the 49ers' injury-riddled season, McCaffrey has been relied on heavily to keep the offense moving. Another heavy workload is in store for the ninth-year veteran when San Francisco heads to Cleveland to face the Browns. The weather forecast calls for strong winds, rain, and snow, which points to an emphasis on the ground game. The Browns had been one of the stronger run defenses in the league, though they have softened as of late. Since their Week 9 bye, Cleveland has given up top-12 finishes in three consecutive weeks to running backs Breece Hall, Derrick Henry, and Ashton Jeanty. McCaffrey is a strong candidate to make it four in a row and should be locked into fantasy football starting lineups for Week 13.
Nov 29, 2025 3:38 AM EST
San Francisco 49ers running back Christian McCaffrey handled another massive workload in Monday night's 20-9 win over the Carolina Panthers, recording 24 carries for 89 yards and a touchdown to go with seven catches (seven targets) for 53 yards in the pass game. McCaffrey now has 298 touches on the season after another 31 in Week 12 against his former team, with Jonathan Taylor being the next closest player at 237. The superstar running back also leads the league in receptions with 81. McCaffrey continues to be one of the top options in all of fantasy football as the engine of San Francisco's offense and a security blanket for quarterback Brock Purdy, who struggled throwing downfield in this game with three interceptions in the first half. McCaffrey will rank as an elite RB1 in Week 13 against the Cleveland Browns.
Nov 25, 2025 12:14 AM EST
San Francisco 49ers running back Christian McCaffrey was the overall RB1 in Week 11, his third such finish in the last five weeks and his tenth top-10 finish in 2025. McCaffrey is in a good spot to attempt a repeat against the Carolina Panthers on Monday night. Much of McCaffrey's production in 2025 has come as a pass-catcher, but with Carolina offering up 4.72 yards per carry to opposing running backs this season, there is reason to believe he will do more damage on the ground than usual in Week 12. Carolina has been especially bad over the last four weeks, giving up a league-worst six rushing touchdowns and the fourth-most fantasy points per game to running backs. It goes without saying that McCaffrey should be in starting lineups in Week 12, but fantasy football managers are justified in feeling especially optimistic about what the superstar will produce in his first game against his former team.
Nov 22, 2025 5:26 AM EST
San Francisco 49ers running back Christian McCaffrey had 13 carries for 81 rushing yards and two rushing touchdowns during Sunday's Week 11 win over the Arizona Cardinals. He also caught five of his six targets for an additional 40 receiving yards and one receiving touchdown. The superstar running back continues to demonstrate excellence as a rusher and receiver, and his big game officially propelled him past Jonathan Taylor for the overall RB1 spot (PPR) through 11 weeks. Given that he was a late-first-round pick in most redraft leagues this year, managers are getting even more than they expected from the 29-year-old. He remains a must-start RB1 for Week 12 against his old team, the Carolina Panthers.
Nov 16, 2025 8:42 PM EST
San Francisco 49ers running back Christian McCaffrey had his second-lowest rushing total of the season in Week 10, gaining just 30 yards on the ground on 12 carries against the Rams. McCaffrey hasn't been as productive in the run game as he has been in years past, averaging 62.6 rushing yards per game in 2025. Still, McCaffrey has been an invaluable fantasy asset thanks to what he has done as a receiver. The double-threat is second in the NFL in receptions behind only Ja'Marr Chase and sixth in receiving yards. In Week 11, McCaffrey will do plenty of damage against the Arizona Cardinals. Last week, Arizona gave up 181 rushing yards and two touchdowns to the Seahawks' running backs. McCaffrey is a regular contender for overall RB1, and his projection for Week 11 is no different.
Nov 15, 2025 4:31 AM EST
San Francisco 49ers running back Christian McCaffrey handled 12 carries for 30 rushing yards and caught eight of his 10 targets for 66 receiving yards in Week 10. As has been the norm this season, McCaffrey's abilities as a receiver kept fantasy football managers happy. He has registered more yards through the air than on the ground in seven of ten games, and Week 10 was the sixth game of the season where he led the team in targets. The 96 scrimmage yards he ground out were his second-lowest total of the season and just the second time in 2025 that he failed to hit the century mark. He should fare better in Week 11 when the 49ers square off against the Arizona Cardinals, who just gave up 181 rushing yards and two touchdowns to Seattle's running backs in Week 10.
Nov 11, 2025 7:39 PM EST
San Francisco 49ers running back Christian McCaffrey took a while to get things going on the ground, but now has reached 100 rushing yards in two of his last three games. However, in the game between, McCaffrey put up his worst numbers of the year in a slog against the Houston Texans. On Sunday, McCaffrey again faces another tough opponent in the Los Angeles Rams. The Rams have allowed the fewest fantasy points per game to opposing running backs, the sixth-fewest rushing yards, and have yet to give up a touchdown on the ground to the position. When the teams met in Week 5, McCaffrey had just 2.6 yards per carry but logged an 8-82-1 line as a receiver. Despite the difficult matchup, McCaffrey's talent makes him a weekly contender to finish as a top-12 back, and he should be locked into fantasy lineups this weekend.
Nov 8, 2025 5:11 AM EST
San Francisco 49ers running back Christian McCaffrey was seemingly unstoppable during Sunday's game against the New York Giants. He got the fun started off early with a five-yard touchdown grab in the first quarter. The Giants defense never seemed to figure out how to stop McCaffrey throughout this game. He rushed 28 times for 106 yards with a touchdown. He also hauled in five of his six targets for 67 yards and an additional score in the victory. McCaffrey posted an ugly outing against the Houston Texans last week, but bounced back nicely here. The 29-year-old remains one of the best fantasy players in the league.
Nov 2, 2025 6:11 PM EST
San Francisco 49ers running back Christian McCaffrey turned in his worst game of the season in Week 8. Against the Texans, McCaffrey toted eight carries for 25 yards and caught three of six targets for 43 receiving yards, all season lows and interrupting his streak of seven consecutive RB1 finishes to start the 2025 season. McCaffrey, being who he is, there is hope for a rebound in Week 9 against the New York Giants. Last week, the Giants gave up 174 scrimmage yards and two touchdowns to Saquon Barkley (groin) in three quarters of work and another 104 rushing yards to backup Tank Bigsby. Unfortunately, San Francisco's offensive line does not compare to Philadelphia's elite unit and will be missing starting center Jake Brendel (hamstring). Still, McCaffrey is one of the league's most dynamic playmakers, and if he is on your fantasy roster, he should be in the starting lineup for Week 9.
Nov 1, 2025 5:18 AM EST
San Francisco 49ers running back Christian McCaffrey rushed for just 25 yards on eight carries during Sunday's Week 8 loss against the Houston Texans. He also caught three of his six targets for an additional 43 receiving yards. McCaffrey had his worst game of the season; his 9.8 points in PPR leagues marked the first time he scored fewer than 22 points in a single game this year. This was a rare dud for McCaffrey, and part of the blame can be attributed to the quarterback position, as Mac Jones (59.4% completion rate, 193 yards, two touchdowns, one interception) struggled to put together many quality drives in place of Brock Purdy (toe). McCaffrey is still one of the most talented running backs in recent NFL history, and he should have no trouble bouncing back against a struggling Giants squad in Week 9.
Oct 26, 2025 8:20 PM EST
San Francisco 49ers running back Christian McCaffrey overcame a challenging matchup last week to eclipse 100 rushing yards in a game for the first time this season. Against the Falcons' surprisingly stout defense, he finished with 129 and two touchdowns on 24 carries, and had another 72 yards through the air on seven catches. Another tough defense awaits McCaffrey and the 49ers in Week 8 against the Houston Texans. Houston has not given up 100 rushing yards to a back yet this year, and is allowing just 3.85 yards per carry. McCaffrey will be hard-pressed to repeat as the overall RB1, but another top-12 finish can be expected given how often San Francisco puts the ball in his hands. Fantasy football managers can ignore the matchup and lock McCaffrey into starting lineups for Week 8.
Oct 25, 2025 5:43 AM EST
The San Francisco 49ers have been as banged up as any team in the NFL this year, but they can beat any team in the league as long as star running back Christian McCaffrey is healthy. McCaffrey once again dominated offensive touches for San Fran in Sunday night's victory over the visiting Atlanta Falcons in Week 7, touching the football 31 times for 201 scrimmage yards and two touchdowns. The 29-year-old do-it-all back had a season-high 24 carries for 129 rushing yards (his first 100-yard game of 2025) and added two rushing scores, as an improved Falcons defense had no answers for him. CMC added seven catches on eight targets for 72 receiving yards. McCaffrey has been the Niners' leading receiver this year and has three receiving touchdowns and three rushing TDs as a balanced offensive threat like few others in the league. Despite another tough test in Week 8 against the Houston Texans' defense, CMC continues to be a must-start, elite RB1 in fantasy football.
Oct 19, 2025 11:44 PM EST
San Francisco 49ers running back Christian McCaffrey appears back on track after a forgettable 2024 campaign. While the 29-year-old is currently averaging a career-low 3.1 yards per carry, he has more than made up for it by catching 46 of his 60 targets for 444 yards and three touchdowns in the 49ers' first six contests. With Brock Purdy (toe) out once again, Mac Jones may continue to look in his direction in the Week 7 meeting with Atlanta. Although the Falcons defense has been formidable this season, that shouldn't deter managers from starting McCaffrey in any fantasy format, especially with this contest projected to be one of the highest-scoring games on the slate.
Oct 17, 2025 10:59 PM EST
San Francisco 49ers running back Christian McCaffrey shouldered another monster workload in his team's 30-19 Week 6 loss to the Tampa Bay Buccaneers. McCaffrey recorded 17 carries for 54 yards, adding seven catches for 57 yards on eight targets as a receiver. The 29-year-old has now topped 100 yards from scrimmage in every game the 49ers have played so far this season. McCaffrey has struggled with rushing efficiency, recording 336 rushing yards and a touchdown on 108 carries (3.1 yards per attempt). However, he's saved his numbers by hauling in 46 catches for 444 yards and three scores. For as long as he's able to stay healthy, McCaffrey is a must-start fantasy running back.
Oct 12, 2025 9:35 PM EST
San Francisco 49ers running back Christian McCaffrey handled 22 carries and caught eight passes for 139 total scrimmage yards in the Niners' 26-23 win over the Rams in Week 5. He is up to five consecutive top-12 finishes among running backs to start the season and leads the league with 130 touches. San Francisco's offense is leaning heavily on McCaffrey as it navigates a myriad of injuries to its star players. Brock Purdy (toe) and Ricky Pearsall (knee) will be shelved for their second consecutive game in Week 6 and both Mac Jones (knee, oblique) and Jauan Jennings (ankle, ribs) are listed as questionable. McCaffrey should see another big workload on Sunday against the Buccaneers and contend for another RB1 finish.
Oct 11, 2025 5:26 AM EST
San Francisco 49ers running back Christian McCaffrey rushed for 57 yards on 22 carries during Thursday's Week 5 win over the Los Angeles Rams. He also caught eight of his nine targets for 82 receiving yards and a receiving touchdown. The superstar running back handled 30 total touches, continuing to prove that he's the only relevant member of the Niners' backfield for the time being. His efficiency on the ground was a little underwhelming, but that didn't stop him from dominating as a pass catcher, per usual. The 29-year-old has exceeded 22.5 fantasy points (PPR) in every game this season, ranking as the overall RB1 to this point. He should be started with full confidence against the Buccaneers in Week 6.
Oct 3, 2025 12:32 AM EST
San Francisco 49ers running back Christian McCaffrey will be relied on to carry the team's offense in Week 5. This is not unusual, but the load will be even heavier (metaphorically, but likely also literally) on Thursday, with wide receivers Ricky Pearsall (knee) and Jauan Jennings (ankle/ribs) declared out due to injuries. Quarterback Brock Purdy (toe) will also be on the sidelines, and cede starting duties to Mac Jones for the third time in four games. McCaffrey has been a force regardless of who is under center, starting the season with four straight top-10 PPR finishes at running back. He has been especially productive through the air, ranking second in the league in targets (43) and eighth in yardage (305). The rest of San Francisco's offense might be falling apart, but for as long as McCaffrey is healthy, he has RB1 potential and should be locked into starting fantasy lineups.
Oct 2, 2025 1:52 AM EST
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