San Francisco 49ers running back Christian McCaffrey (back) was removed from the Week 18 injury report on Thursday and will play on Saturday night against the division-rival Seattle Seahawks, according to Jennifer Lee Chan of NBC Sports Bay Area. McCaffrey has dealt with a bit of back stiffness in the final month of the regular season, but it hasn't been a serious issue, and he'll be fine this weekend as the Niners look to secure the No. 1 seed, a first-round bye, and home-field advantage throughout the postseason. The 29-year-old is coming off a second straight 100-yard rushing game in the Week 17 win over the Chicago Bears on Sunday night, in which he had 23 carries for a season-high 140 yards and one touchdown on the ground. CMC added 41 receiving yards on four catches. He remains the do-it-all focal point of San Fran's offense and is a must-start, high-end RB1 in all fantasy leagues in Week 18.
Jan 1, 2026 6:31 PM EST
San Francisco 49ers general manager John Lynch said on KNBR Radio on Wednesday that star running back Christian McCaffrey (back) is "trending to play" on Saturday night for the divisional clash against the Seattle Seahawks in the Week 18 regular-season finale, according to Cam Inman of the Bay Area News Group. Tight end George Kittle (ankle) is expected to be available, too, after missing the Week 17 win over the Chicago Bears. Back stiffness kept McCaffrey from practicing on Tuesday, but he's expected to return Wednesday or Thursday and play this weekend in a massive game that will decide the No. 1 seed in the NFC going into the playoffs next week. CMC had a season-high 140 rushing yards and a touchdown on Sunday night against Chicago, and despite a tough matchup against Seattle, he's a no-doubt, must-start in all fantasy lineups. McCaffrey has 20-plus touches in five straight games.
Dec 31, 2025 12:54 PM EST
San Francisco 49ers running back Christian McCaffrey (back) did not practice on Tuesday due to a back injury, according to Matt Barrows of The Athletic. McCaffrey dealt with back stiffness earlier this month, too, but he didn't miss any time. The 29-year-old's back injury isn't very serious this time around, either, and it shouldn't keep him from playing a big role in a crucial divisional battle this Saturday night against the Seattle Seahawks that will determine the No. 1 seed in the NFC playoff picture. CMC was unstoppable in Sunday night's win over the Chicago Bears, going for a season-high 140 rushing yards and a touchdown on 23 rushing attempts. He also caught four of six targets for 41 yards as a receiver. McCaffrey won't find running room as easily to come by against Seattle, but he should still be considered a high-end RB1 option for fantasy managers still playing for something in Week 18.
Dec 30, 2025 6:50 PM EST
San Francisco 49ers running back Christian McCaffrey has finished outside of the top ten at his position just twice in 2025. The heart of San Francisco's offense, McCaffrey leads the team in targets per game, is averaging 125.9 scrimmage yards per game, and has scored a touchdown in all but four of the 49ers' games this season. CMC's role in the passing game regressed in recent weeks until his 6-29-2 line on eight targets in Week 16. His target share may remain elevated in Week 17, as tight end George Kittle (ankle) is a game-time decision and Ricky Pearsall (knee, ankle) is questionable. McCaffrey has a welcome matchup against the Bears in Week 17. Chicago has allowed the sixth-most rushing yards per game and the second-most rushing yards before contact per attempt this year. As always, McCaffrey is in contention for an RB1 finish and should be locked into lineups for the final weekend of the fantasy football season.
Dec 27, 2025 4:04 AM EST
San Francisco 49ers running back Christian McCaffrey had another explosive performance in Week 16. McCaffrey ran for 117 yards on 21 carries and caught six of his eight targets for 29 yards and two touchdowns in the 49ers' 48-27 win over the Colts on Monday night. It was one of McCaffrey's better running performances of the season, having averaged 3.6 yards per carry coming into the game. McCaffrey's recent downward trend in receiving yards continued, though he was back to being one of the team's leaders in targets, due in part to Ricky Pearsall's (knee, ankle) absence. McCaffrey is now 151 yards away from achieving 1,000 yards in the rushing and receiving categories for the second time in his career. His next opportunity to add to his total will be against the Bears, who have allowed their opponents 348.1 offensive yards per game.
Dec 23, 2025 2:11 PM EST
San Francisco 49ers running back Christian McCaffrey will put a four-game touchdown streak on the line in Week 16 against the Colts. Last week, Indianapolis held Seahawks running backs Kenneth Walker III and Zach Charbonnet out of the end zone, but had given up at least one rushing touchdown to a running back in each of their six previous games. McCaffrey appears to be clear of the back injury that made him a surprising late addition to the 49ers' injury report last week, and should see plenty of work on Monday night. If Ricky Pearsall (knee/ankle) is unable to play, then CMC would likely reemerge as a candidate to lead the team in targets, as he has done six times already in 2025. Fantasy football managers should watch for the 49ers' final injury report, but assuming McCaffrey is fully healthy, he has the potential for a top-3 finish at his position.
Dec 20, 2025 6:03 AM EST
San Francisco 49ers running back Christian McCaffrey (back) popped up on Saturday's injury report with a back issue, but he looked healthy handling 22 carries for 73 yards and a touchdown in Sunday's win over the Titans. McCaffrey also caught his lone target of the day for 14 receiving yards. The reduction in pass volume was stark compared to the 8.2 targets he averaged before the 49ers' Week 14 bye, but it may have been a small act towards preserving the playmaker's health. McCaffrey will get an extra day of rest going into Week 16, as the 49ers will square off against the Colts on Monday night. Concern over McCaffrey's back makes Brian Robinson Jr. a must-stash as he would likely step into a bellcow role if CMC sits. Assuming McCaffrey is healthy, he will once again be a must-start in the semi-final round of the fantasy football playoffs.
Dec 16, 2025 6:21 PM EST
Per the team, San Francisco 49ers running back Christian McCaffrey (back, illness) will be active for Week 15's home matchup with the Tennessee Titans. Fresh off a bye week, the fantasy stalwart gave owners a scare after coming down with an illness. A late-week back issue offered no solace, but it appears that McCaffrey will be out there despite just one full practice this week. Fantasy managers can exhibit no worries slotting him into their lineups, as it doesn't appear he's in any danger of playing less than his typical allotment of snaps. McCaffrey is an elite RB1 option, and, officially, RotoBaller's PPR RB1 in this week's rankings.
Dec 14, 2025 3:12 PM EST
San Francisco 49ers running back Christian McCaffrey (back) "should be good to go" for Sunday's Week 15 contest against the Tennessee Titans, according to Ian Rapoport of NFL.com. McCaffrey entered the weekend without an injury designation, but he was added to the injury report on Saturday with a questionable tag. In the end, the star running back is expected to suit up in a very favorable matchup against a struggling Titans run defense that has allowed the third-most rushing touchdowns to opposing running backs in 2025. If he's near 100 percent, McCaffrey will rank as a high-end RB1 in fantasy football.
Dec 14, 2025 7:50 AM EST
San Francisco 49ers running back Christian McCaffrey (back) popped up on the injury report on Saturday due to a back issue. According to Adam Schefter, McCaffrey is expected to suit up for the Week 15 matchup against the Tennessee Titans. This issue doesn't appear to be severe enough to keep McCaffrey on the sideline. If he suffers a setback, Brian Robinson Jr. and Isaac Guerendo would likely split up a majority of the snaps in the backfield. Fantasy managers should expect McCaffrey out there on Sunday, but there probably won't be official word until closer to kickoff. The 49ers don't play until 4:25 pm ET, so his official announcement might not be made until sometime in the afternoon.
Dec 13, 2025 6:15 PM EST
San Francisco 49ers running back Christian McCaffrey (back) has been added back to the Week 15 injury report and is now listed as questionable for Sunday's game against the Tennessee Titans due to a back injury, according to Matt Barrows of The Athletic. It's a concerning sign to see the superstar back be added to the Week 15 injury report this late in the week, so his status needs to be monitored up until gametime on Sunday. McCaffrey has handled the biggest workload in the league this season with 322 touches in 13 games and has arguably been the best player in fantasy football. Fantasy managers should rush to pick up Brian Robinson Jr. if he is available, as he would be in line for a workhorse role on Sunday in a solid matchup against the Titans if McCaffrey ends up being ruled out.
Dec 13, 2025 4:19 PM EST
San Francisco 49ers running back Christian McCaffrey (illness) gave fantasy football managers a scare when he popped up on the team's injury report earlier this week, raising concern over his availability in Week 15. Fortunately, McCaffrey got in a full session on Friday and has been cleared for Sunday. CMC will be able to take advantage of an inviting matchup against the Titans, who have given up 4.49 yards per carry and 17 total touchdowns to running backs in 2025. San Francisco's offense has run through McCaffrey this season, who not only has the third-most rushing attempts in the NFL (237) but also ranks fifth in receptions (85). McCaffrey has finished as a top-12 running back in 12 of the 49ers' 13 games, and he will be in the mix again in the first round of the fantasy football playoffs.
Dec 13, 2025 5:26 AM EST
San Francisco 49ers running back Christian McCaffrey (illness) was a full-go in practice on Friday and was removed from the Week 15 injury report, according to Cam Inman of the Bay Area News Group. McCaffrey is fully expected to play on Sunday against the visiting Tennessee Titans after he came down with an illness this week and was limited in practice on Thursday. CMC is an absolute must-start in Week 15 against the Titans, a team that allows 122.5 rushing yards per game. The 29-year-old comes into Week 15 action as the RB2 in half-PPR points on the year, thanks to 849 rushing yards and eight touchdowns on 237 carries. McCaffrey hasn't been that great on the ground, but where he excels is as a pass-catcher, as he leads all backs in catches (85), targets (107), receiving yards (806), and touchdowns (five), and it's not even close.
Dec 12, 2025 7:25 PM EST
San Francisco 49ers running back Christian McCaffrey (illness) was a limited participant during practice on Thursday. This was an improvement in status for McCaffrey, who missed practice entirely on Wednesday. He's trending in the right direction to play against the Tennessee Titans in Week 15, but managers should check back on Friday for additional confirmation on his status. If he's able to practice in full, he could avoid any sort of injury designation heading into the weekend. However, if he remains limited, the 49ers may list him as questionable. With that being said, the fact that McCaffrey was able to get on the field in some capacity on Thursday bodes well for his Week 15 availability. If active, he'll rank as a high-end RB1 against the Titans, who have allowed the 10th-most fantasy points to running backs in 2025.
Dec 11, 2025 8:45 PM EST
San Francisco 49ers running back Christian McCaffrey handled 20 carries for 53 yards and a touchdown in the team's 26-8 win over the Browns in Week 13. He also caught all four of his targets for 21 receiving yards. Sunday's game was just the third time this season that McCaffrey finished with fewer than 100 scrimmage yards, and his four targets were a season low. Still, the two-time All-Pro finished as a top-12 running back in PPR scoring for the twelfth time in 13 weeks. Fantasy football managers will have to do without McCaffrey's services in Week 14 while the 49ers are on bye. Those lucky enough to have sewn up a spot in the fantasy football playoffs get to look forward to a matchup against the Titans in Week 15.
Dec 2, 2025 4:21 PM EST
San Francisco 49ers running back Christian McCaffrey enters Week 13 leading the NFL in touches (298) and second in receptions (81). Amid the 49ers' injury-riddled season, McCaffrey has been relied on heavily to keep the offense moving. Another heavy workload is in store for the ninth-year veteran when San Francisco heads to Cleveland to face the Browns. The weather forecast calls for strong winds, rain, and snow, which points to an emphasis on the ground game. The Browns had been one of the stronger run defenses in the league, though they have softened as of late. Since their Week 9 bye, Cleveland has given up top-12 finishes in three consecutive weeks to running backs Breece Hall, Derrick Henry, and Ashton Jeanty. McCaffrey is a strong candidate to make it four in a row and should be locked into fantasy football starting lineups for Week 13.
Nov 29, 2025 3:38 AM EST
San Francisco 49ers running back Christian McCaffrey handled another massive workload in Monday night's 20-9 win over the Carolina Panthers, recording 24 carries for 89 yards and a touchdown to go with seven catches (seven targets) for 53 yards in the pass game. McCaffrey now has 298 touches on the season after another 31 in Week 12 against his former team, with Jonathan Taylor being the next closest player at 237. The superstar running back also leads the league in receptions with 81. McCaffrey continues to be one of the top options in all of fantasy football as the engine of San Francisco's offense and a security blanket for quarterback Brock Purdy, who struggled throwing downfield in this game with three interceptions in the first half. McCaffrey will rank as an elite RB1 in Week 13 against the Cleveland Browns.
Nov 25, 2025 12:14 AM EST
San Francisco 49ers running back Christian McCaffrey was the overall RB1 in Week 11, his third such finish in the last five weeks and his tenth top-10 finish in 2025. McCaffrey is in a good spot to attempt a repeat against the Carolina Panthers on Monday night. Much of McCaffrey's production in 2025 has come as a pass-catcher, but with Carolina offering up 4.72 yards per carry to opposing running backs this season, there is reason to believe he will do more damage on the ground than usual in Week 12. Carolina has been especially bad over the last four weeks, giving up a league-worst six rushing touchdowns and the fourth-most fantasy points per game to running backs. It goes without saying that McCaffrey should be in starting lineups in Week 12, but fantasy football managers are justified in feeling especially optimistic about what the superstar will produce in his first game against his former team.
Nov 22, 2025 5:26 AM EST
San Francisco 49ers running back Christian McCaffrey had 13 carries for 81 rushing yards and two rushing touchdowns during Sunday's Week 11 win over the Arizona Cardinals. He also caught five of his six targets for an additional 40 receiving yards and one receiving touchdown. The superstar running back continues to demonstrate excellence as a rusher and receiver, and his big game officially propelled him past Jonathan Taylor for the overall RB1 spot (PPR) through 11 weeks. Given that he was a late-first-round pick in most redraft leagues this year, managers are getting even more than they expected from the 29-year-old. He remains a must-start RB1 for Week 12 against his old team, the Carolina Panthers.
Nov 16, 2025 8:42 PM EST
San Francisco 49ers running back Christian McCaffrey had his second-lowest rushing total of the season in Week 10, gaining just 30 yards on the ground on 12 carries against the Rams. McCaffrey hasn't been as productive in the run game as he has been in years past, averaging 62.6 rushing yards per game in 2025. Still, McCaffrey has been an invaluable fantasy asset thanks to what he has done as a receiver. The double-threat is second in the NFL in receptions behind only Ja'Marr Chase and sixth in receiving yards. In Week 11, McCaffrey will do plenty of damage against the Arizona Cardinals. Last week, Arizona gave up 181 rushing yards and two touchdowns to the Seahawks' running backs. McCaffrey is a regular contender for overall RB1, and his projection for Week 11 is no different.
Nov 15, 2025 4:31 AM EST
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