Who Should I Start? Brandon Aiyuk or Michael Wilson

Tuesday, August 26, 5:06 PM

The San Francisco 49ers officially placed wide receiver Brandon Aiyuk (knee) on the Reserve/Physically Unable to Perform list to begin the 2025 season, which means he will miss at least the first four contests. Head coach Kyle Shanahan has already said that Aiyuk might be targeting a return around Week 6 on the road against the Tampa Bay Buccaneers. The 27-year-old suffered a torn ACL and MCL in Week 7 of last season, which is why he's not ready for the start of 2025. The former first-round wideout had been a major disappointment in fantasy before his season-ending knee injury, too, as he caught just 25 of 47 targets for 374 yards and didn't find the end zone once in seven games. It's understandable for fantasy managers to want to avoid him altogether this year, although he's still worth drafting in leagues with IR spots. With Aiyuk sidelined, Jauan Jennings (calf) and Ricky Pearsall should serve as the top wideouts in San Fran.

Thursday, August 7, 6:24 PM

Arizona Cardinals wide receiver Michael Wilson (concussion) was out of his non-contact jersey during Thursday's training camp practice, according to Tyler Drake of Arizona Sports. Wilson didn't take any contact in practice, but it's a good sign that he's on his way to being removed from the injury report, and he could play in the preseason opener this Saturday against the Kansas City Chiefs. Nothing from Wilson's first two seasons in the NFL suggests that he's ready for a breakout in 2025 in his third year, as he has totaled 85 receptions for 1,113 yards and seven touchdowns in 29 games (25 starts) in his first two years. The former third-rounder in 2023 out of Stanford will be a distant No. 3 target for quarterback Kyler Murray behind Marvin Harrison Jr. and tight end Trey McBride. If either of the two miss time with an injury, though, Wilson will be a popular waiver-wire pickup.