Who Should I Start? Brandon Aiyuk or Michael Wilson

Wednesday, November 5, 6:04 PM

San Francisco 49ers head coach Kyle Shanahan said on Wednesday that he's "pretty confident" that wide receiver Brandon Aiyuk (knee) will play at some point this season, according to David Lombardi of The San Francisco Standard. However, the 49ers are still waiting for Aiyuk to "hit certain markers" on GPS speed measurements before opening his 21-day practice window. Once Aiyuk returns to practice, the team will have 21 days to officially activate him from the Physically Unable to Perform list. Despite the optimism, reports on Monday suggested that the 27-year-old former first-rounder wasn't close to a return to practice, so fantasy managers who have been stashing Aiyuk all year shouldn't get their hopes up. Aiyuk suffered a torn ACL and MCL in Week 7 of last year and probably won't be back in games for the 49ers until December.

Wednesday, November 5, 2:17 PM

Arizona Cardinals wide receiver Michael Wilson has emerged as a go-to weapon in the passing game with Jacoby Brissett under center. Brissett continues to heap praise on the young receiver, stating, "If need be, he could be the No. 1 target." The passing game has continued to improve with Brissett under center, with Wilson and Marvin Harrison Jr. finally living up to their potential. Despite the praise, you should proceed with caution for Wilson in a Week 10 matchup with a stingy Seattle Seahawks defense that has allowed the eighth-fewest fantasy points to wide receivers this season.