Who Should I Start? Brandon Aiyuk or Ricky Pearsall

Thursday, December 18, 4:18 PM

San Francisco 49ers head coach Kyle Shanahan said that wide receiver Brandon Aiyuk (knee) has been "extremely distant" from the team since suffering a season-ending knee injury in Week 7 of the 2024 season, per Matt Barrows of The Athletic. The 27-year-old has not played a game since that point. The 49ers voided guarantees in his contract for 2026 and placed him on the reserve/left squad list on Saturday, officially ending his 2025 season. All signs seem to indicate that Aiyuk and the 49ers are likely to go their separate ways this offseason. In his last fully healthy season in 2023, Aiyuk recorded 75 receptions for 1,342 yards and seven touchdowns on 105 targets. He has a chance to get back to his superstar heights if he can get fully healthy and find the right team. However, his health and the way his current situation in San Francisco has unfolded may bring about question marks for dynasty league fantasy managers.

Wednesday, January 7, 3:07 PM

San Francisco 49ers wide receiver Ricky Pearsall (knee, ankle) will not practice on Wednesday, according to head coach Kyle Shanahan. Pearsall aggravated a PCL sprain in his right knee and was held out of the Week 18 regular-season finale against the Seattle Seahawks last Saturday. The 25-year-old former first-rounder missed a good chunk of the 2025 season due to his knee injury, so he could be fighting an uphill battle to play on Wild-Card weekend in Philadelphia against the Eagles on Sunday. If Pearsall cannot get cleared to play in the opening round of the playoffs, it will open up targets for receivers Jauan Jennings, Demarcus Robinson, and Kendrick Bourne, as well as tight end George Kittle. In the Week 18 loss to Seattle, Jennings led the team with four catches for only 35 yards. As of right now, Pearsall is likely on the wrong side of questionable to play against Philly.