Should I Start Deebo Samuel Sr.?

Friday, September 25, 3:32 PM

San Francisco 49ers wide receiver Deebo Samuel Sr. has elevated fantasy value ahead of his team's divisional standoff against the Arizona Cardinals. The veteran wideout has had a modest return to the Bay Area, with nine catches on 11 targets for 79 yards and one touchdown, plus two carries, to start his 2026 campaign. His target share should increase in Week 3, however, with fellow receivers Mike Evans (hip) listed as questionable, and Demarcus Robinson (ankle) and De'Zhaun Stribling (ankle) both out. Arizona has allowed 24 receptions for 329 yards and four touchdowns by wide receivers to start the season, which boosts Samuel's appeal. He is a solid WR3 and flex option going up against the Cardinals at home.