Who Should I Start? Christian McCaffrey or Darnell Mooney

Sunday, September 14, 8:39 PM

San Francisco 49ers running back Christian McCaffrey rushed for 55 yards on 13 carries during Sunday's Week 2 victory over the New Orleans Saints. He also caught six of seven targets for an additional 53 receiving yards and one receiving touchdown. Although the veteran playmaker didn't quite eclipse the 100-yard mark, he made up for it by scoring his first touchdown of the 2025 campaign. He also served as a very valuable and dependable pass-catching option for quarterback Mac Jones amidst the injury to Brock Purdy (shoulder). McCaffrey has wasted no time making a big impact in fantasy football, scoring at least 22.7 points (PPR) in each of his first two games this year. There's minimal competition for the 29-year-old in San Francisco, keeping him in the mid-range RB1 tier ahead of Week 3 versus the Arizona Cardinals.

Saturday, September 13, 10:47 AM

Atlanta Falcons wide receiver Darnell Mooney (shoulder) was a full participant in practice on Friday after being limited earlier in the week, and heads into Sunday night's matchup with the Vikings without an injury designation. The 27-year-old should slide back into his role as No. 2 receiver behind Drake London (shoulder), who also practiced fully on Friday. Mooney owned a solid 21.3 percent target share last season with the same receiving corps, although much of that was with Kirk Cousins under center. In the two games he played with Michael Penix Jr. at the helm, Mooney's target share dropped to 17.7 percent. Going up against a tough run defense, the Falcons may prefer to attack Minnesota through the air, but with plenty of receiving options at their disposal and Mooney potentially getting eased back into action, the sixth-year pro should be viewed as a high-end WR4/Flex play in Week 2 with some slight upside in PPR formats.