Who Should I Start? Christian McCaffrey or Kyren Williams

Thursday, January 1, 6:31 PM

San Francisco 49ers running back Christian McCaffrey (back) was removed from the Week 18 injury report on Thursday and will play on Saturday night against the division-rival Seattle Seahawks, according to Jennifer Lee Chan of NBC Sports Bay Area. McCaffrey has dealt with a bit of back stiffness in the final month of the regular season, but it hasn't been a serious issue, and he'll be fine this weekend as the Niners look to secure the No. 1 seed, a first-round bye, and home-field advantage throughout the postseason. The 29-year-old is coming off a second straight 100-yard rushing game in the Week 17 win over the Chicago Bears on Sunday night, in which he had 23 carries for a season-high 140 yards and one touchdown on the ground. CMC added 41 receiving yards on four catches. He remains the do-it-all focal point of San Fran's offense and is a must-start, high-end RB1 in all fantasy leagues in Week 18.

Friday, January 2, 3:15 PM

Los Angeles Rams running back Kyren Williams (ankle) is officially questionable to play in his team's Week 18 matchup against the Arizona Cardinals, per Adam Grosbard of the Los Angeles Daily News. Williams suffered an ankle injury during the Rams' Week 17 loss to the Atlanta Falcons, but was able to return to the game. Los Angeles could be locked into the number six seed in the NFC come game time on Sunday, but Rams head coach Sean McVay said on Friday that he plans to play the team's starters regardless. Rams running back Blake Corum (ankle) is also questionable to play in Week 18, so Williams could be in line to dominate backfield snaps against Arizona if Corum is sidelined. If both Williams and Corum are inactive, the team would likely split work between veteran back Ronnie Rivers and rookie Jarquez Hunter.