Who Should I Start? Christian McCaffrey or Marlon Mack

Saturday, October 17, 1:15 PM

San Francisco 49ers running back Christian McCaffrey had 68 rushing yards and a touchdown on 11 carries and three catches for 15 receiving yards on five targets last week. In Week 6, the 49ers face the Commanders, who have been surprisingly effective against the run. Washington has allowed just two rushing touchdowns, the sixth-fewest rushing yards, and the fourth-fewest fantasy points to opposing running backs in 2026. McCaffrey's utility as a receiver will keep him in play as a top option at his position. The Commanders are in the middle of the pack defending against passes to running backs, and Deebo Samuel Sr. (hamstring) has been ruled out, and Mike Evans (ribs, Achilles) is questionable, which means more targets could come CMC's way. McCaffrey projects as an RB1 and should be started in fantasy football in Week 6.