Who Should I Start? Christian McCaffrey or Patrick Mahomes

Thursday, November 14, 8:03 PM

San Francisco 49ers running back Christian McCaffrey (Achilles) was limited for the second straight day in practice this week on Thursday. McCaffrey made his 2024 debut in the Week 10 win over the Tampa Bay Buccaneers but will most likely continue to have his workload monitored in practice the rest of the season. In his debut last Sunday, the 28-year-old All-Pro back had 19 touches for 107 scrimmage yards while playing 88 percent of the offensive snaps. We'd expect CMC to be removed from the final Week 11 injury report and be San Fran's lead back in a divisional clash against the Seattle Seahawks. Backups Jordan Mason and Isaac Guerendo had a combined two carries for five yards in McCaffrey's return. McCaffrey will be looking to build on his debut last week and is a must-start in all fantasy lineups.

Friday, November 15, 4:00 PM

Kansas City Chiefs quarterback Patrick Mahomes will face the Buffalo Bills in Week 11. The 29-year-old found himself on the injury report with an ankle/hip injury but practiced fully all week and has been removed from the injury report ahead of the contest. Mahomes was trending up until he faced the tough Denver Broncos defense in Week 10. Mahomes passed for 266 yards and one touchdown in last week's contest at Arrowhead. The Chiefs quarterback will now take on a Buffalo Bills defense ranked fifth in fantasy points allowed to opposing quarterbacks this season. Despite these teams being two high-powered passing offenses in the past, this game has the makings of a defensive showdown. Kansas City and Buffalo have strong defenses and an affinity for running the ball to dominate time of possession. This week, Mahomes is ranked QB13 in our RotoBaller rankings, placing him outside QB1 territory. Fantasy managers may be disappointed with Mahomes if this contest turns into a defensive affair.