Who Should I Start? DeAndre Hopkins or Christian McCaffrey

Saturday, September 13, 7:47 AM

Baltimore Ravens wide receiver DeAndre Hopkins proved why he's a three-time All-Pro with an amazing one-handed grab against the Buffalo Bills for a touchdown. While his days of 100+ targets per season are in the rearview mirror, he can still play that outlet role whenever called upon. The biggest issue for fantasy managers is that it's nearly impossible to predict which games he'll be more involved in compared to the others. In Week 2, he'll go up against the Cleveland Browns, who do have a better and more aggressive defensive unit. Hopkins might be viable in very deep leagues, but he likely won't receive more targets than Mark Andrews again, which would leave him around fourth in the target pecking order. So managers in 12-team leagues can safely leave him on the bench.

Sunday, September 14, 8:39 PM

San Francisco 49ers running back Christian McCaffrey rushed for 55 yards on 13 carries during Sunday's Week 2 victory over the New Orleans Saints. He also caught six of seven targets for an additional 53 receiving yards and one receiving touchdown. Although the veteran playmaker didn't quite eclipse the 100-yard mark, he made up for it by scoring his first touchdown of the 2025 campaign. He also served as a very valuable and dependable pass-catching option for quarterback Mac Jones amidst the injury to Brock Purdy (shoulder). McCaffrey has wasted no time making a big impact in fantasy football, scoring at least 22.7 points (PPR) in each of his first two games this year. There's minimal competition for the 29-year-old in San Francisco, keeping him in the mid-range RB1 tier ahead of Week 3 versus the Arizona Cardinals.