Who Should I Start? Derrick Henry or Joe Mixon

Saturday, October 4, 2:05 PM

Even without MVP quarterback Lamar Jackson (hamstring), Baltimore Ravens running back Derrick Henry still should be considered an RB1 candidate when his team takes on the Houston Texans in Week 5. The veteran running back is coming off a low-volume dud last week during a blowout loss at Kansas City, but should be the focal point of the Baltimore offense on Sunday. Houston allows opponents to score at the lowest rate in the NFL, but is only middle of the pack against fantasy running backs. The Ravens will need Henry to be involved early and often, which should keep him locked into fantasy lineups.

Tuesday, October 7, 11:41 AM

Houston Texans general manager Nick Caserio said the team will have clarity on running back Joe Mixon's (foot/ankle) health status for the "duration of the year" at some point "over the next few weeks." Mixon has not played yet in 2025, and the team has provided little to no information about a possible return timeline. It seems possible, if not likely, that the 29-year-old will miss the entirety of the season. If that's the case, Houston will likely continue splitting backfield work between veteran Nick Chubb and rookie Woody Marks. Chubb has recorded 58 carries for 249 yards and two touchdowns so far this season. Marks has logged 233 yards from scrimmage and two touchdowns on 42 total touches, and could eventually work his way into the lead role over the course of the season.