Who Should I Start? George Holani or Dylan Sampson

Sunday, November 23, 2:30 PM

Seattle Seahawks running back George Holani (hamstring) has been ruled out for the remainder of his team's Week 12 matchup against the Tennessee Titans due to a hamstring injury. The 25-year-old did not record a carry or earn a target before exiting the game. Holani plays the RB3 role in Seattle behind Kenneth Walker III and Zach Charbonnet. Without Holani, Walker III and Charbonnet will now handle all of the Seahawks' backfield work for the remainder of Week 12. More information on the severity of Holani's injury should come following the game.

Friday, November 28, 9:24 PM

Cleveland Browns running back Dylan Sampson turned in one of his team's best plays in a Week 12 win over the Las Vegas Raiders when he hauled in a 66-yard touchdown pass from Shedeur Sanders in the fourth quarter. While he hasn't seen a consistent workload this season, Sampson has shown chops in the passing game, catching 23 passes for 195 yards and two touchdowns in 11 games. In Week 13, Sampson will look to stay hot at home against the San Francisco 49ers. The 49ers have been solid against the run this season, allowing just the 19th-most fantasy points per game to running backs. While not a safe fantasy play, Sampson sets up as an RB5 with some flex appeal for Week 13's matchup.