Who Should I Start? Isaac Guerendo or Cam Skattebo

Friday, June 6, 12:54 PM

San Francisco 49ers running back Isaac Guerendo (ankle, knee) has been taking part in voluntary organized team activities this spring after injuring his MCL and spraining his ankle in the Week 18 regular-season finale last year. Guerendo, a fourth-round pick (129th overall) in 2024, should be a full-go for the start of mandatory minicamp on June 10. All-Pro Christian McCaffrey (knee) is also back and ready to roll after missing the majority of the 2024 campaign, so Guerendo will enter the 2025 season as the backup, but Jordan Mason was traded to the Minnesota Vikings and Elijah Mitchell left in free agency. The 24-year-old Guerendo had 5.0 yards per carry on his 84 rushing attempts last year for 420 yards and four touchdowns in 16 games (three starts), adding 15 catches for 152 yards through the air. Consider him a high-upside handcuff behind the injury-prone CMC.

Wednesday, June 18, 2:46 PM

New York Giants running back Cam Skattebo has agreed to terms on his rookie deal and is set to officially sign on Wednesday, according to NFL insider Mike Garafolo. The fourth-round pick out of Arizona State carries plenty of fantasy football intrigue after a monster collegiate career of production. He began his career at Sacramento State before joining the Sun Devils' program in 2023. As a senior in 2024, Skattebo rushed 293 times for 1,711 yards and caught 45 passes for 605 yards. Overall, he tallied 2,316 yards from scrimmage and 24 touchdowns. Although 2024 rookie Tyrone Tracy Jr. impressed in his first year of action, the two could be in a committee backfield in 2025, though Devin Singletary is still on the roster. All that said, Skattebo has workhorse size and could carve out a significant role with volume in 2025 or 2026.