Who Should I Start? Isaac Guerendo or Nicholas Singleton

BENCH

Week 1 Projections

Fant.
Pts.		 Rush.
Yds.		 Rush
TD		 Rec. Rec.
Yds.		 Rec
TD
0.0 0.0 0.0 0.0 0.0 0.0

Isaac Guerendo News

Isaac Guerendo Placed on PUP List, Out for Four Games

Sunday, August 30, 3:42 PM

San Francisco 49ers running back Isaac Guerendo (pectoral) has been placed on the Physically Unable to Perform list, according to Jeremy Fowler of ESPN.com. He will now miss at least four games, keeping him sidelined through the entire month of September. At the earliest, he can return in Week 5 against the Seattle Seahawks on October 11. Guerendo did not play an offensive snap last year, but he was heavily involved as the primary backup to Christian McCaffrey in 2024. That year, he tallied 420 rushing yards, 152 receiving yards, and four touchdowns. There's a chance that Guerendo could return to that level of production (and his role as the No. 2 ball-carrier) once he's healthy again, but in the meantime, Kaelon Black and Jordan James will round out the depth chart behind McCaffrey.

START

Week 1 Projections

Fant.
Pts.		 Rush.
Yds.		 Rush
TD		 Rec. Rec.
Yds.		 Rec
TD
1.2 6.2 0.1 0.1 1.2 0.0

Nicholas Singleton News

Nicholas Singleton Should be Ignored in Starting Week 1 Lineups

Saturday, September 12, 9:24 AM

Tennessee Titans rookie running back Nicholas Singleton, the 165th overall pick in the 2026 NFL draft in April in the fifth round from Penn State, enters his first year in the NFL as the team's No. 3 RB behind Tony Pollard and Tyjae Spears. Singleton is not rostered in most standard-sized, single-year fantasy leagues, but an injury to either Pollard or Spears could quickly make him attractive off the waiver wire in the Titans' new-look offense this year under coordinator Brian Daboll. The 22-year-old had two 1,000-yard rushing campaigns in his four collegiate seasons with the Nittany Lions and added 45 rushing touchdowns in 53 total games. He was also proficient as a receiver out of the backfield, catching 102 passes for 987 yards and another nine touchdowns as a pass-catcher. A broken foot limited him to 549 rushing yards in his senior season, but he still added a career-high 13 touchdowns on the ground. Singleton is fully healthy now as Tennessee's RB3, but he should be on benches in deeper fantasy leagues for his NFL debut against the New York Jets this Sunday.

Isaac Guerendo vs. Nicholas Singleton

Still trying to decide between Guerendo and Singleton? Check on the latest news to make sure both players are active and healthy. Our PPR projections show that Isaac Guerendo is projected to score 0.0 points this week while Nicholas Singleton is projected to score 1.2 points.