Who Should I Start? Isaac Guerendo or Omarion Hampton

Monday, December 22, 7:11 PM

San Francisco 49ers running back Jordan James is active for Monday's Week 16 contest against the Indianapolis Colts and is on track to make his NFL debut. The rookie had previously been a healthy scratch, but he's getting a chance to play on primetime television, perhaps in a mix of special teams and offensive depth roles. He's taking the spot of fellow rookie Isaac Guerendo, who is a healthy scratch for the first time in his young career. Guerendo has contributed on special teams this year, but he doesn't have an offensive snap yet. Both running backs remain buried on the depth chart behind Christian McCaffrey and Brian Robinson Jr.

Thursday, January 8, 6:19 PM

Updating a previous report, Los Angeles Chargers rookie first-round running back Omarion Hampton (ankle) was listed as a non-participant at practice for the second straight day on Thursday, according to the team. Offensive coordinator Greg Roman said earlier in the day that Hampton would be "involved some" in practice, but apparently that wasn't the case. The Bolts held the 22-year-old out in the Week 18 regular-season finale against the Denver Broncos, along with a lot of their starters, but he's now officially up in the air to be ready to go for Sunday night's Wild-Card clash against the New England Patriots. We'll have a better idea of Hampton's status on Friday, but as of right now, he's a starting RB trending down in a bad matchup. If Hampton is out or limited at all this weekend, Kimani Vidal would jump into RB1 territory for the volume boost alone.