Who Should I Start? Isaac Guerendo or Woody Marks

Saturday, September 6, 6:51 AM

Second-year running back Isaac Guerendo opens the season third on the 49ers' depth chart, though he may already see more action than originally anticipated. Christian McCaffrey (calf) popped up on the team's injury report this week and is tagged as questionable for San Francisco's Week 1 matchup against the Seahawks. Guerendo's only route to fantasy relevance relies on CMC sitting. If that does happen, then he can be seen as a deep-league flex candidate. Brian Robinson Jr. will likely draw the start, but Guerendo made his mark in 2024 in similar circumstances and is a potential RB4/5 pending McCaffrey's status.

Friday, September 5, 10:23 PM

Houston Texans running back Woody Marks will make his NFL debut on Sunday afternoon when the Texans head to SoFi Stadium to take on the Rams. Marks is expected to be the team's top receiving-down back and could play his way into a larger role with Nick Chubb and Dameon Pierce also expected to be involved while Joe Mixon (ankle) is on the reserve/non-football injury list. Marks was a fourth-round pick for the Texans out of USC, and he racked up 63 rushing yards and a touchdown on 16 carries, along with four catches for 20 yards this preseason. He worked mostly behind Pierce and Chubb, but depending on the game script, he could be a sneaky FLEX play down the road. In Week 1, he's the RB60 in RotoBaller's rankings, so he isn't a good start just yet, although he's a strong stash based on his long-term outlook and potential upside.