Who Should I Start? Isaac Guerendo or Woody Marks

Tuesday, October 21, 9:16 PM

San Francisco 49ers running back Isaac Guerendo was thrust into action in his rookie season in the NFL in 2024 because Christian McCaffrey missed most of the year due to injuries. Guerendo finished with 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) and also chipped in 15 catches on 16 targets as a pass-catcher for 152 yards. Fantasy managers probably viewed him as a pretty valuable handcuff for the injury-prone CMC going into 2025 drafts, but the Niners' acquisition of Brian Robinson Jr. before the season pretty much killed whatever fantasy appeal he had. Through the first seven weeks of his sophomore campaign, the 25-year-old former fourth-rounder has yet to play an offensive snap with CMC and B-Rob both staying healthy. Instead, Guerendo has been limited to a special teams role, returning five kickoffs for a combined 100 yards.

Friday, December 12, 9:57 PM

Houston Texans running back Woody Marks (knee) missed some practice earlier this week but does not have an injury designation and is ready to go for the Texans' Week 15 matchup against Arizona. The Cardinals have allowed 18 running back touchdowns in 13 games, including eight in the last four weeks. Marks could get more of the workload with Nick Chubb (ribs, questionable) banged up. Marks checks in as the No. 17 RB in RotoBaller's Week 15 rankings, so he's a strong RB2 play this week after setting a new career-high with 26 carries last week. He scored his fifth touchdown of the season in the Texans' win over the Chiefs, and he has a much better matchup this week, giving him a good ceiling, especially if he gets all the work in this favorable matchup. He crushed the Titans as the focal point of the offense in a similar scenario earlier this season, and he's a strong start in Week 15.