Who Should I Start? Isaac Guerendo or Woody Marks

Monday, January 6, 10:31 PM

An MRI exam on Monday morning revealed that San Francisco 49ers rookie running back Isaac Guerendo (ankle, knee) suffered an MCL sprain and an ankle sprain in the loss to the division-rival Arizona Cardinals on Sunday in the Week 18 regular-season finale, according to a source. Guerendo will have plenty of time to heal up in the offseason, and the best news is that he didn't suffer any damage to his ACL. Both of the injuries are to his left leg. The 24-year-old fourth-round pick didn't see much of an opportunity in 2024 until late in the season when both Christian McCaffrey (knee) and Jordan Mason (ankle) were ruled out for the year, but when he did get his chances, he was pretty effective out of the Niners' backfield. Guerendo finished with 5.0 yards per carry for 420 yards and four TDs on 84 carries through 16 games. He should serve as valuable insurance for McCaffrey in 2025.

Sunday, May 11, 9:02 PM

The Houston Texans have signed fourth-round rookie running back Woody Marks to a four-year, $5.2 million deal. Houston traded up to acquire the rights to the USC alum, sending a future third-rounder to the Miami Dolphins. Marks was a four-year player at Mississippi State and a prolific pass-catcher, particularly in his first two collegiate seasons when he totaled 143 receptions, 770 yards, and three touchdowns. He slowed down from there, but still caught at least 47 balls in two of his final three campaigns, including his last at USC. The 24-year-old isn't a burner, but don't confuse him with an early-down thumper. He's a decisive runner who trusts his blocking and possesses enough burst and shake to get to and through the second level consistently. Teammate Joe Mixon is the unquestioned RB1 in Houston, but there's little reason to think Marks couldn't challenge for backup duties. Due to his prowess as a receiver out of the backfield, seeing him garner snaps in those situations early on wouldn't be surprising.