Who Should I Start? Isiah Pacheco or James Cook

Thursday, February 5, 11:28 AM

After an injury-marred campaign in 2024, Kansas City Chiefs running back Isiah Pacheco entered 2025 in need of a bounce-back effort. Unfortunately, the 26-year-old struggled with inefficiency, recording 563 scrimmage yards and two touchdowns on 137 touches across 13 games played. Pacheco averaged just 3.9 yards per carry, his second-straight season under four yards per rush attempt after averaging 4.7 yards per carry over the first two years of his career. Pacheco spent most of the 2025 season splitting backfield work with veteran Chiefs running back Kareem Hunt, with Hunt dominating touches in short-yardage situations and around the goal line. Pacheco is now set to hit unrestricted free agency, so he's not guaranteed to be back in Kansas City. Based on his performance over the last two seasons, it's not hard to imagine a scenario where Pacheco finds himself in a committee backfield or even a straight RB2 role for the 2026 season. In dynasty formats, Pacheco's future fantasy value profiles as uncertain at best coming off his shaky 2025 campaign.

Friday, February 13, 7:31 AM

Buffalo Bills running back James Cook III solidified himself as one of the NFL's best running backs in 2025, racking up 1,621 rushing yards and 12 touchdowns on 309 carries across 17 games. The 26-year-old also impacted the game as a receiver, hauling in 33 receptions for 291 yards and two scores. Cook III has always been an efficient player, but he was able to reach new production heights in 2025 thanks to an increase in workload. After logging 239 touches across 16 games played in 2024, Cook III recorded 342 touches in 2025 and still averaged a highly efficient 5.6 yards per touch. Cook III signed a four-year extension with Buffalo before the start of the 2025 season, so he's locked in as the team's lead rusher for the foreseeable future. The Bills also promoted former offensive coordinator Joe Brady to head coach, so it seems unlikely that the team would radically shift its offensive approach going forward. Now that he's proven he can handle a significant workload, Cook III profiles as a high-end running back option for fantasy managers in dynasty formats.