Who Should I Start? Jacoby Brissett or Baker Mayfield

Sunday, October 12, 9:25 PM

Arizona Cardinals quarterback Jacoby Brissett did an admirable job filling in for the injured Kyler Murray (foot) in his team's 31-27 Week 6 loss to the Indianapolis Colts. Brissett completed 27 of 44 pass attempts for 320 yards, two touchdowns, and one interception. The 32-year-old also rushed three times for 19 yards. With Murray currently battling a mid-foot sprain, there's a chance Brissett could have an extended runway as the starter in Arizona. Brissett started five games for the New England Patriots in 2024, completing 59% of his passes for 826 yards, two touchdowns, and one interception. If he is forced into action once again, Brissett has a tough matchup in Week 7 against the Green Bay Packers. Still, he could be a valuable pickup for fantasy managers in two-quarterback formats.

Sunday, October 12, 9:52 PM

Tampa Bay Buccaneers quarterback Baker Mayfield led his team to its fifth win of the season in Week 6, beating the San Francisco 49ers 30-19. Mayfield completed 17 of his 23 pass attempts for 256 yards and two touchdowns without throwing an interception and added 14 rushing yards on three carries. The 30-year-old has now thrown for 1,309 yards and 12 touchdowns in his first six games of 2025. Tampa Bay entered Week 6 without wide receivers Mike Evans (hamstring), Chris Godwin (leg), and Jalen McMillan (neck), and then lost star rookie wideout Emeka Egbuka (hamstring) to a hamstring injury during the game. It's currently unclear how long the Buccaneers will be without their top four wide receivers. Regardless, Mayfield has proven himself to be a worthy fantasy QB1 on a week-to-week basis.