Who Should I Start? Jacoby Brissett or Caleb Williams

Friday, October 16, 10:38 PM

Arizona Cardinals quarterback Jacoby Brissett threw for a season-high 292 yards and three touchdowns last week. Trailing for most of the game, Brissett threw 47 passes (completing 29) in the lopsided loss to the Detroit Lions. It was a high point on a roller coaster season for Brissett, who has averaged 283 yards per game in three weeks but has a combined 261 in his other two. As 12.5-point underdogs against the Rams in Week 6, Arizona can be expected to lean heavily into the pass once again. The Rams' defense will present a much greater challenge than the Lions' did in Week 5, though. Los Angeles has not allowed more than 215 passing yards in a game thus far in 2026. Brissett's relentlessness (he ranks fourth in pass attempts per game with 39.8) keeps him in the running as a qualified streamer in two-QB leagues in Week 6.