Who Should I Start? James Conner or Omarion Hampton

Monday, September 22, 6:34 PM

Arizona Cardinals running back James Conner (ankle) underwent season-ending surgery on Monday after suffering a significant right ankle injury in the third quarter of Sunday's game. Conner was carted off with his ankle immobilized, and head coach Jonathan Gannon confirmed he won't return this season. With Conner sidelined, the Cardinals will turn to second-year back Trey Benson, who has been highly efficient, averaging 6.0 yards per carry (second among RBs). Gannon praised Benson before the season, noting he viewed both Conner and Benson as capable starters. Benson now projects as the lead option in Arizona's backfield, while Emari Demercado is expected to mix in behind him.

Sunday, October 12, 9:16 AM

Los Angeles Chargers running back Omarion Hampton (ankle) is expected to spend more than the minimum four weeks on injured reserve, according to Mike Garafolo of NFL Network. The injury that the rookie suffered in Week 5 appears to be serious enough that he'll be out through at least Week 10, and perhaps longer. The Chargers have a Week 12 bye, so it wouldn't be surprising to see Los Angeles hold him out until Week 13, giving him an extra week off to rest. Losing both Hampton and Najee Harris (Achilles) is a major blow for the Chargers, who will turn to Hassan Haskins and Kimani Vidal but could also look to make external running back additions.