Who Should I Start? Joe Mixon or James Conner

Wednesday, January 21, 12:19 PM

Houston Texans general manager Nick Caserio said on Wednesday that running back Joe Mixon (foot, ankle) had a medical condition that never improved, according to Jonathan M. Alexander of the Houston Chronicle. "He didn't jump off a building. He wasn't doing anything irresponsible. It was a freak thing," Caserio said. The Texans were extremely vague with Mixon's injury all year, and he never ended up playing in 2025. Head coach DeMeco Ryans said on Monday that Mixon's status for the 2026 season is also uncertain due to his injury. Unexpectedly, the Texans struggled for consistent production out of their backfield with a mix of veteran Nick Chubb and Woody Marks. Marks took over halfway through the year and should be heavily involved again next season, even if Mixon returns. Needless to say, a lot of fantasy managers won't want anything to do with Mixon in 2026.

Friday, January 30, 3:31 PM

Arizona Cardinals running back James Conner (ankle) had his 2025 season cut short when he suffered a season-ending ankle injury in Week 3. The veteran running back was a productive player as recently as 2024, when he recorded 1,508 scrimmage yards and nine touchdowns on 283 touches across 16 games played. However, he will enter the 2026 season at 31 years old and less than a year removed from significant ankle surgery, bringing his future fantasy viability into question. The Cardinals spent most of the 2025 season without both of their top running backs, as 2024 third-round pick Trey Benson (knee) did not play after Week 4 due to a knee injury. While Benson's injury status clouds his future outlook as well, Arizona appears headed for a backfield split. The team could also bring in additional talent at the position through free agency or the draft heading into 2026. Given his age and unclear health status, Conner's fantasy value in both redraft and dynasty formats is currently trending in the wrong direction.