Who Should I Start? Joe Mixon or James Conner

Wednesday, January 21, 12:19 PM

Houston Texans general manager Nick Caserio said on Wednesday that running back Joe Mixon (foot, ankle) had a medical condition that never improved, according to Jonathan M. Alexander of the Houston Chronicle. "He didn't jump off a building. He wasn't doing anything irresponsible. It was a freak thing," Caserio said. The Texans were extremely vague with Mixon's injury all year, and he never ended up playing in 2025. Head coach DeMeco Ryans said on Monday that Mixon's status for the 2026 season is also uncertain due to his injury. Unexpectedly, the Texans struggled for consistent production out of their backfield with a mix of veteran Nick Chubb and Woody Marks. Marks took over halfway through the year and should be heavily involved again next season, even if Mixon returns. Needless to say, a lot of fantasy managers won't want anything to do with Mixon in 2026.

Monday, September 22, 6:34 PM

Arizona Cardinals running back James Conner (ankle) underwent season-ending surgery on Monday after suffering a significant right ankle injury in the third quarter of Sunday's game. Conner was carted off with his ankle immobilized, and head coach Jonathan Gannon confirmed he won't return this season. With Conner sidelined, the Cardinals will turn to second-year back Trey Benson, who has been highly efficient, averaging 6.0 yards per carry (second among RBs). Gannon praised Benson before the season, noting he viewed both Conner and Benson as capable starters. Benson now projects as the lead option in Arizona's backfield, while Emari Demercado is expected to mix in behind him.