Who Should I Start? Joe Mixon or Jaylen Warren

Thursday, November 20, 12:34 PM

Houston Texans running back Joe Mixon (ankle, foot) is not expected to play this season as he deals with a foot injury from the offseason, according to Ian Rapoport of NFL Network. Mixon will likely stay on the Physically Unable to Perform list through the end of the 2025 season, while the Texans move forward with veteran Nick Chubb and rookie Woody Marks in their backfield. Things had been trending this way for a while, as the Texans haven't been giving any real updates on Mixon for pretty much the entire season. Fantasy managers who are still stashing the 29-year-old in redraft leagues should send him to the waiver wire now. Mixon's injury dates all the way back to spring workouts. One would think he'd be ready for the start of the 2026 campaign, but there has been little information about the exact nature of his injury. Marks, a fourth-rounder in April, has slowly started to see more work and should be the backfield leader over Chubb by the end of the year.

Monday, December 15, 7:43 PM

Pittsburgh Steelers running back Jaylen Warren (illness), who was a late addition to the Week 15 injury report due to an illness, is officially active for the Monday night game against the visiting Miami Dolphins, according to Teresa Varley of Steelers.com. Fantasy managers can leave the 27-year-old in their starting lineups, but Warren may be spelled a bit more by backfield mate Kenneth Gainwell against Miami. Warren has been Pittsburgh's primary RB all year and is averaging 12.0 half-PPR fantasy points per game on 652 rushing yards and four touchdowns on 159 rushing attempts. He's added 30 receptions for 277 yards and another two scores as a receiver. Warren has a pretty high ceiling as an RB2, as he's had double-digit touches in all 12 of his games in 2025 while averaging 15.8 touches and 77.4 scrimmage yards.