Who Should I Start? Joe Mixon or Saquon Barkley

Wednesday, January 21, 12:19 PM

Houston Texans general manager Nick Caserio said on Wednesday that running back Joe Mixon (foot, ankle) had a medical condition that never improved, according to Jonathan M. Alexander of the Houston Chronicle. "He didn't jump off a building. He wasn't doing anything irresponsible. It was a freak thing," Caserio said. The Texans were extremely vague with Mixon's injury all year, and he never ended up playing in 2025. Head coach DeMeco Ryans said on Monday that Mixon's status for the 2026 season is also uncertain due to his injury. Unexpectedly, the Texans struggled for consistent production out of their backfield with a mix of veteran Nick Chubb and Woody Marks. Marks took over halfway through the year and should be heavily involved again next season, even if Mixon returns. Needless to say, a lot of fantasy managers won't want anything to do with Mixon in 2026.

Thursday, January 8, 10:57 AM

Philadelphia Eagles running back Saquon Barkley finished the 2025 season with 1413 scrimmage yards and nine touchdowns on 317 total attempts. After totaling nearly 2,300 scrimmage yards in 2024, Barkley regressed, dropping from 5.8 yards per carry to 4.1 this season. Despite the Eagles' offensive struggles this season, they are in the playoffs and hosting the San Francisco 49ers in the Wild Card Round. The 49ers allowed the 10th-most fantasy points to running backs this season, and injuries to their defensive line and linebackers should open up lanes for Barkley. The defending champions relied heavily on their star running back in last year's Super Bowl run, and they are expected to do the same as they chase back-to-back Super Bowl titles.