Who Should I Start? Kyler Murray or Trey McBride

Monday, October 6, 10:59 PM

Arizona Cardinals head coach Jonathan Gannon said that quarterback Kyler Murray (foot) will be monitored this week after briefly leaving the Week 5 loss to the Tennessee Titans on Sunday to have his foot evaluated in the locker room, according to Darren Urban of AZCardinals.com. The fact that Murray returned and finished out Sunday's game should give fantasy managers hope that he'll be able to play in Week 6 against the Indianapolis Colts. However, Gannon is leaving things up in the air early in the week, so we'll have to pay close attention to the 28-year-old signal-caller's practice status later in the week. Murray had another middling fantasy outing against the Titans, throwing for 220 yards, no touchdowns, and no interceptions. He added a rushing touchdown but also lost a fumble. If Murray is unable to play in Week 6, veteran Jacoby Brissett would make the start against the one-loss Colts.

Saturday, October 4, 12:50 PM

Arizona Cardinals tight end Trey McBride has been the clear number one option in the passing game for Cardinals quarterback Kyler Murray so far in 2025. Through four games, McBride has recorded 24 catches for 234 yards and a touchdown on 35 targets. The 25-year-old has a favorable matchup in Week 5 against the Tennessee Titans. Tennessee's defense ranks in the bottom 10 in the NFL in yards per pass attempt allowed (7.4), and Titans opponents are averaging 30 points per game. In Week 5, McBride is a must-start fantasy tight end.