Who Should I Start? Matthew Stafford or Dak Prescott

Saturday, November 8, 2:08 PM

Los Angeles Rams quarterback Matthew Stafford is having one of the best seasons of his career, and he remains a must-start fantasy quarterback in Week 10 against the San Francisco 49ers despite his limited rushing upside. Stafford now has 16 touchdowns and zero interceptions over his last five games, leading the Rams to a 6-2 start while supporting big fantasy performances from Puka Nacua, Davante Adams, and Kyren Williams. Stafford himself is the overall QB9 so far, and he's fourth in the MVP race with +500 odds. He has become matchup-proof this season and should be started against all opponents. With that said, a matchup against the San Francisco 49ers certainly doesn't hurt. The Niners have allowed the ninth-most fantasy points to opposing quarterbacks in 2025 and have forced just one interception. Stafford racked up 389 yards and three touchdowns when he faced the 49ers earlier this season.

Tuesday, November 4, 12:40 AM

Dallas Cowboys quarterback Dak Prescott completed 24 of 39 pass attempts for 250 yards, one touchdown, and one interception while adding 34 yards on four carries in Monday night's 27-17 loss to the Cardinals. Prescott struggled a bit in this game, taking five sacks for a loss of 40 yards and turning it over on downs three times. The interception came at the very end of the game on a desperation heave on a 4th and 28. The 32-year-old led the offense to only 10 points, as the Cowboys scored one of their two touchdowns on a blocked punt. Prescott was able to at least salvage decent fantasy days for his top three pass catchers in CeeDee Lamb, George Pickens, and Jake Ferguson. Prescott and the Cowboys will head into their Week 10 bye on a two-game losing streak.