Who Should I Start? Najee Harris or Isaac Guerendo

Monday, April 28, 11:53 PM

While nothing is set in stone right now, Los Angeles Chargers head coach Jim Harbaugh said that the team plans to deploy a booming 1-2 punch with rookie running back Omarion Hampton and Najee Harris in 2025. True to the Harbaugh mentality, the Bolts plan to line up and run the ball with Hampton and Harris, who are both big and powerful backs. Harbaugh raved about Hampton's ability to break tackles -- According to Pro Football Focus, 2,505 of his career rushing yards at North Carolina came after contact. At No. 22 overall in the first round of the 2025 NFL draft last Thursday, Hampton was a "unanimous" decision for the Chargers. Hampton averaged 5.9 yards per carry in each of his last two seasons with the Tar Heels and was a true workhorse. While his fantasy upside will be limited while sharing the backfield with Harris in 2025, Hampton's long-term fantasy upside in Harbaugh's system has to excite those in dynasty formats.

Friday, June 6, 12:54 PM

San Francisco 49ers running back Isaac Guerendo (ankle, knee) has been taking part in voluntary organized team activities this spring after injuring his MCL and spraining his ankle in the Week 18 regular-season finale last year. Guerendo, a fourth-round pick (129th overall) in 2024, should be a full-go for the start of mandatory minicamp on June 10. All-Pro Christian McCaffrey (knee) is also back and ready to roll after missing the majority of the 2024 campaign, so Guerendo will enter the 2025 season as the backup, but Jordan Mason was traded to the Minnesota Vikings and Elijah Mitchell left in free agency. The 24-year-old Guerendo had 5.0 yards per carry on his 84 rushing attempts last year for 420 yards and four touchdowns in 16 games (three starts), adding 15 catches for 152 yards through the air. Consider him a high-upside handcuff behind the injury-prone CMC.