Who Should I Start? Najee Harris or Isaac Guerendo

Wednesday, September 24, 6:15 PM

The Los Angeles Chargers announced on Wednesday that they placed running back Najee Harris (Achilles) on Injured Reserve, according to Fernando Ramirez of the Sporting Tribune. Harris' season is over after he tore his Achilles in the Week 3 win over the Denver Broncos on Sunday. It's a disappointing end to his first year with the Bolts after signing with them in free agency in the offseason. The 27-year-old will end his streak of four straight 1,000-yard rushing seasons to begin his career. In his three games this year, Harris carried the ball 15 times for 61 yards and no touchdowns, adding three receptions for 25 yards through the air. The Chargers will be forced to lean more on rookie first-rounder Omarion Hampton as their lead back going forward, making him a must-start each week. Hassan Haskins will be elevated to the RB2 role, with Kimani Vidal the next man up at No. 2 in the backfield.

Wednesday, October 8, 11:50 AM

San Francisco 49ers running back Isaac Guerendo recorded 572 yards from scrimmage and four touchdowns on 99 total touches as a rookie in 2024. However, through five games in 2025, the 25-year-old has not played a single offensive snap. Guerendo is buried on the 49ers running back depth chart behind Christian McCaffrey and Brian Robinson Jr. As long as both McCaffrey and Robinson Jr. remain healthy, it appears unlikely that Guerendo's role in San Francisco's offense is going to change. Guerendo maintains some appeal in dynasty leagues, but he should remain off the radar of redraft fantasy managers for the time being.