Should I Start Jacoby Brissett?

Saturday, September 26, 12:28 PM

Arizona Cardinals quarterback Jacoby Brissett had a rough day in his team's Week 2 loss to the Seattle Seahawks, throwing for just 95 yards, one touchdown, and one interception on 28 pass attempts. However, the veteran signal-caller was significantly better in Arizona's season opener, throwing for 277 yards and a touchdown against the Los Angeles Chargers. In Week 3, Brissett will take on a San Francisco 49ers defense that currently ranks 14th in the NFL in yards per pass attempt allowed (7.2) and has allowed just one receiving touchdown per game. The 49ers will be without star defensive end Nick Bosa (calf, knee), which should give Brissett more time to make plays. Brissett may also be forced to turn to the air early and often if the Cardinals defense cannot slow down the potent 49ers offense. In his lone start against San Francisco in 2025, the 33-year-old threw for 452 yards and two touchdowns on 57 pass attempts. All in all, Brissett profiles as a low-end QB2 option for fantasy managers in Week 3.