Who Should I Start? Samaje Perine or Isaac Guerendo

Thursday, May 1, 3:25 PM

Cincinnati Bengals running back Samaje Perine is expected to have a lesser version of the two-minute, passing-down role that he held near the end of his first tenure with the organization, according to Paul Dehner Jr. of The Athletic. Perine spent the 2020, 2021, and 2022 seasons with the Bengals and secured 38 receptions in his final season with the team. After a year with Denver and a year with Kansas City, he's back in Joe Burrow's offense and will have somewhat of a role in the backfield. However, the 29-year-old is likely well past his prime, and Chase Brown showed enough to have confidence in him as a starting fantasy football running back in 2025. Either way, Perine could be worth rostering in deeper PPR setups based on this report.

Friday, June 6, 12:54 PM

San Francisco 49ers running back Isaac Guerendo (ankle, knee) has been taking part in voluntary organized team activities this spring after injuring his MCL and spraining his ankle in the Week 18 regular-season finale last year. Guerendo, a fourth-round pick (129th overall) in 2024, should be a full-go for the start of mandatory minicamp on June 10. All-Pro Christian McCaffrey (knee) is also back and ready to roll after missing the majority of the 2024 campaign, so Guerendo will enter the 2025 season as the backup, but Jordan Mason was traded to the Minnesota Vikings and Elijah Mitchell left in free agency. The 24-year-old Guerendo had 5.0 yards per carry on his 84 rushing attempts last year for 420 yards and four touchdowns in 16 games (three starts), adding 15 catches for 152 yards through the air. Consider him a high-upside handcuff behind the injury-prone CMC.