Who Should I Start? Samaje Perine or Isaac Guerendo

Thursday, May 1, 3:25 PM

Cincinnati Bengals running back Samaje Perine is expected to have a lesser version of the two-minute, passing-down role that he held near the end of his first tenure with the organization, according to Paul Dehner Jr. of The Athletic. Perine spent the 2020, 2021, and 2022 seasons with the Bengals and secured 38 receptions in his final season with the team. After a year with Denver and a year with Kansas City, he's back in Joe Burrow's offense and will have somewhat of a role in the backfield. However, the 29-year-old is likely well past his prime, and Chase Brown showed enough to have confidence in him as a starting fantasy football running back in 2025. Either way, Perine could be worth rostering in deeper PPR setups based on this report.

Monday, January 6, 10:31 PM

An MRI exam on Monday morning revealed that San Francisco 49ers rookie running back Isaac Guerendo (ankle, knee) suffered an MCL sprain and an ankle sprain in the loss to the division-rival Arizona Cardinals on Sunday in the Week 18 regular-season finale, according to a source. Guerendo will have plenty of time to heal up in the offseason, and the best news is that he didn't suffer any damage to his ACL. Both of the injuries are to his left leg. The 24-year-old fourth-round pick didn't see much of an opportunity in 2024 until late in the season when both Christian McCaffrey (knee) and Jordan Mason (ankle) were ruled out for the year, but when he did get his chances, he was pretty effective out of the Niners' backfield. Guerendo finished with 5.0 yards per carry for 420 yards and four TDs on 84 carries through 16 games. He should serve as valuable insurance for McCaffrey in 2025.